Natural killer (NK) cells contribute to the first line of defense against viruses and to the control of tumor growth and metastasis spread. The discovery of HLA class I specific …
Natural killer (NK) cells are innate lymphocytes that are crucial for the control of infections and malignancies. NK cells express a variety of inhibitory and activating receptors that …
Natural killer (NK) cells play critical roles in immune defense and reproduction, yet remain the most poorly understood major lymphocyte population. Because their activation is …
V Béziat, LL Liu, JA Malmberg… - Blood, The Journal …, 2013 - ashpublications.org
Human natural killer (NK) cells are functionally regulated by killer cell immunoglobulin-like receptors (KIRs) and their interactions with HLA class I molecules. As KIR expression in a …
P Parham, A Moffett - Nature Reviews Immunology, 2013 - nature.com
Natural killer (NK) cells have roles in immunity and reproduction that are controlled by variable receptors that recognize MHC class I molecules. The variable NK cell receptors …
Our understanding of development and function of natural killer (NK) cells has progressed significantly in recent years. However, exactly how uterine NK (uNK) cells develop and …
L Abi-Rached, MJ Jobin, S Kulkarni, A McWhinnie… - Science, 2011 - science.org
Whole genome comparisons identified introgression from archaic to modern humans. Our analysis of highly polymorphic human leukocyte antigen (HLA) class I, vital immune system …
SE Hiby, R Apps, AM Sharkey… - The Journal of …, 2010 - Am Soc Clin Investig
Many common disorders of pregnancy are attributed to insufficient invasion of the uterine lining by trophoblast, fetal cells that are the major cell type of the placenta. Interactions …
Stimulation or tolerance of natural killer (NK) cells is achieved through a cross‐talk of signals derived from cell surface activating and inhibitory receptors. Killer cell immunoglobulin‐like …