Are We Ready for Life in the Fast Lane? A Critical Review of Preoperative Hypofractionated Radiotherapy for Localized Soft Tissue Sarcoma

BA Guadagnolo, EH Baldini - Seminars in radiation oncology, 2024 - Elsevier
This critical review aims to summarize the relevant published data regarding
hypofractionation regimens for preoperative radiation therapy (RT) prior to surgery for soft …

Hypofractionated preoperative radiation therapy for soft tissue sarcoma: a systematic review

R Joyce, E Herlihy, N Lavan, C Gillham - International Journal of Radiation …, 2024 - Elsevier
Purpose Hypofractionated radiation therapy is being used more frequently for many
common cancer sites. Conventionally fractionated radiation therapy treatment regimens …

Preoperative dose-escalated intensity-modulated radiotherapy (IMRT) and intraoperative radiation therapy (IORT) in patients with retroperitoneal soft-tissue sarcoma …

K Seidensaal, M Dostal, A Kudak, C Jaekel, E Meixner… - Cancers, 2023 - mdpi.com
Simple Summary Retroperitoneal sarcomas represent a very rare entity. The most common
pattern of recurrence and cause of death is local recurrence, and the rates of locoregional …

[HTML][HTML] Novel Postoperative Hypofractionated Accelerated Radiation Dose-Painting Approach for Soft Tissue Sarcoma

M Mills, J Miller, C Liveringhouse, JM Bryant… - Advances in Radiation …, 2024 - Elsevier
Purpose Hypofractionated radiation therapy (RT) offers benefits in the treatment of soft tissue
sarcomas (STS), including exploitation of the lower α/β, patient convenience, and cost. This …

The incidence, risk factors and outcomes of wound complications after preoperative radiotherapy and surgery for high grade extremity soft tissue sarcomas: A 14-year …

Z Ouyang, S Trent, C McCarthy, T Cosker… - European Journal of …, 2023 - Elsevier
Objective The aim of this study was to analyze the wound complication (WC) rate and to
determine the risk factors for WC in patients with soft tissue sarcoma treated with …

[HTML][HTML] Preoperative Ultrahypofractionated Radiation Therapy for Soft Tissue Sarcomas: Low Rate of Wound Complications

A Mattmann, C Glanzmann, B Fuchs, B Bode… - Advances in Radiation …, 2024 - Elsevier
Purpose Normofractionated preoperative radiation therapy (nRT) with 50 Gy applied in 25
fractions represents the most widely used radiation therapy (RT) regimen in combined local …

[HTML][HTML] Is hypofractionated radiotherapy used to treat soft tissue sarcomas? Assessment of practices using the NETSARC network

E Agnoux, A Stefani, N Sahki, É Meknaci… - Cancer …, 2024 - Elsevier
Purpose Extremity soft-tissue sarcomas are treated by wide surgical resection with
normofractionated radiotherapy. Over the past 3 years, several phase II trials emerged on …

Adopting shorter radiation regimens: rules of engagement for sarcoma

A Kalbasi - The Lancet Oncology, 2023 - thelancet.com
B Ashleigh Guadagnolo and colleagues1 deserve high praise for conducting the largest
prospective radiotherapy trial for patients with sarcoma since NCIC-SR2, which shows that …

Radiotherapy innovation in rare diseases-focusing on the value of single institutional experiences for hypofractionated radiotherapy in soft tissue sarcoma

ZS Mayo, N Mesko, L Nystrom, CS Shah… - Radiotherapy and …, 2023 - thegreenjournal.com
We note the interest by Hsu and Kao in our recent publication [1]. This single institutional
series is a contribution to the growing literature of hypofractionated preoperative …