Chorioallantoic membrane assay as model for angiogenesis in tissue engineering: Focus on stem cells

G Merckx, H Tay, M Lo Monaco… - … Engineering Part B …, 2020 - liebertpub.com
Tissue engineering aims to structurally and functionally regenerate damaged tissues, which
requires the formation of new blood vessels that supply oxygen and nutrients by the process …

Microvascular experimentation in the chick chorioallantoic membrane as a model for screening angiogenic agents including from gene-modified cells

DC Kennedy, B Coen, AM Wheatley… - International journal of …, 2021 - mdpi.com
The chick chorioallantoic membrane (CAM) assay model of angiogenesis has been
highlighted as a relatively quick, low cost and effective model for the study of pro-angiogenic …

SERCA overexpression improves mitochondrial quality control and attenuates cardiac microvascular ischemia-reperfusion injury

Y Tan, D Mui, S Toan, P Zhu, R Li, H Zhou - Molecular Therapy-Nucleic …, 2020 - cell.com
Despite significant advances in the treatment of myocardial ischemia-reperfusion (I/R) injury,
coronary circulation is a so far neglected target of cardioprotection. In this study, we …

hESCs‐derived early vascular cell spheroids for cardiac tissue vascular engineering and myocardial infarction treatment

Y Liu, Y Zhang, T Mei, H Cao, Y Hu, W Jia… - Advanced …, 2022 - Wiley Online Library
Transplanting functional cells to treat myocardial infarction (MI), a major disease threatening
human health, has become the focus of global therapy. However, the efficacy has not been …

Resveratrol improves Bnip3-related mitophagy and attenuates high-fat-induced endothelial dysfunction

C Li, Y Tan, J Wu, Q Ma, S Bai, Z Xia, X Wan… - Frontiers in Cell and …, 2020 - frontiersin.org
Statin treatment reduces cardiovascular risk. However, individuals with well-controlled low-
density lipoprotein (LDL) levels may remain at increased risk owing to persistent high …

Human cardiac organoids for modeling genetic cardiomyopathy

M Filippo Buono, L von Boehmer, J Strang… - Cells, 2020 - mdpi.com
Genetic cardiomyopathies are characterized by changes in the function and structure of the
myocardium. The development of a novel in vitro model could help to better emulate healthy …

Microvessels derived from hiPSCs are a novel source for angiogenesis and tissue regeneration

X Gao, S Ma, X Xing, J Yang, X Xu… - Journal of Tissue …, 2022 - journals.sagepub.com
The establishment of effective vascularization represents a key challenge in regenerative
medicine. Adequate sources of vascular cells and intact vessel fragments have not yet been …

[HTML][HTML] Photobiomodulation therapy at red and near-infrared wavelengths for osteogenic differentiation in the scaffold-free microtissues

ZBY Çevik, O Karaman, N Topaloğlu - Journal of Photochemistry and …, 2023 - Elsevier
One of the novel strategies for bone tissue regeneration is photobiomodulation (PBM) which
depends on the red and near-infrared light absorption by mitochondria and may trigger bone …

Adipose tissue and the vascularization of biomaterials: stem cells, microvascular fragments and nanofat—a review

P Kamat, FS Frueh, M McLuckie, N Sanchez-Macedo… - Cytotherapy, 2020 - Elsevier
Tissue defects in the human body after trauma and injury require precise reconstruction to
regain function. Hence, there is a great demand for clinically translatable approaches with …

Caveolin‐1 knockdown increases the therapeutic sensitivity of lung cancer to cisplatin‐induced apoptosis by repressing Parkin‐related mitophagy and activating the …

Y Liu, Y Fu, X Hu, S Chen, J Miao… - Journal of Cellular …, 2020 - Wiley Online Library
Chemotherapy is the first‐line treatment option for patients with lung cancer. However,
therapeutic resistance occurs through an incompletely understood mechanism. Our …