The respiratory surface in the mammalian lung is stabilized by pulmonary surfactant, a
membrane-based system composed of multiple lipids and specific proteins, the primary …

Pulmonary surfactant is a lipid/protein complex synthesized by the alveolar epithelium and
secreted into the airspaces, where it coats and protects the large respiratory air–liquid …

Surfactant proteins A (SP-A) and D (SP-D) have been implicated in pulmonary innate
immunity. The proteins are host defense lectins, belonging to the collectin family which also …

Derangement in pulmonary surfactant or its components and alveolar collapse are common
findings in idiopathic pulmonary fibrosis (IPF). Surfactant proteins play important roles in …

The respiratory epithelium has evolved to produce a complicated network of extracellular
membranes that are essential for breathing and, ultimately, survival. Surfactant membranes …

Soluble defense collagens form a group of secreted proteins that are primarily involved in
host defense. All defense collagens contain a globular recognition domain contiguous to a …

The human innate host defense molecules, SP-A1 and SP-A2 variants, differentially affect
survival after infection in mice and in lung transplant patients. SP-A interacts with the …

Animal Lectins: Form, Function and Clinical Applications presents up-to-date knowledge of
animal lectins. Detailed descriptions on biological activities, tissue and/or subcellular …

Surfactant protein A (SP-A) enhances phagocytosis of Pseudomonas aeruginosa. SP-A1
and SP-A2 encode human (h) SP-A; SP-A2 products enhance phagocytosis more than SP …

Surfactant protein A (SP-A) plays an important role in host defense, modulation of
inflammatory processes, and surfactant-related functions of the lung. The human SP-A (hSP …