Protein assembly: versatile approaches to construct highly ordered nanostructures

Q Luo, C Hou, Y Bai, R Wang, J Liu - Chemical Reviews, 2016 - ACS Publications
Nature endows life with a wide variety of sophisticated, synergistic, and highly functional
protein assemblies. Following Nature's inspiration to assemble protein building blocks into …

Glycomimetics versus multivalent glycoconjugates for the design of high affinity lectin ligands

S Cecioni, A Imberty, S Vidal - Chemical reviews, 2015 - ACS Publications
One could certainly highlight a conceptual resemblance between social interactions as the
basis of societies and civilizations and the ability of molecules to interact in a noncovalent …

Multivalent glycoconjugates as anti-pathogenic agents

A Bernardi, J Jiménez-Barbero, A Casnati… - Chemical Society …, 2013 - pubs.rsc.org
Multivalency plays a major role in biological processes and particularly in the relationship
between pathogenic microorganisms and their host that involves protein–glycan recognition …

Carbohydrates in supramolecular chemistry

M Delbianco, P Bharate, S Varela-Aramburu… - Chemical …, 2016 - ACS Publications
Carbohydrates are involved in a variety of biological processes. The ability of sugars to form
a large number of hydrogen bonds has made them important components for …

Bridging lectin binding sites by multivalent carbohydrates

V Wittmann, RJ Pieters - Chemical Society Reviews, 2013 - pubs.rsc.org
Carbohydrate–protein interactions are involved in a multitude of biological recognition
processes. Since individual protein–carbohydrate interactions are usually weak …

Antimicrobial activity of calixarenes and related macrocycles

DN Shurpik, PL Padnya, II Stoikov, PJ Cragg - Molecules, 2020 - mdpi.com
Calixarenes and related macrocycles have been shown to have antimicrobial effects since
the 1950s. This review highlights the antimicrobial properties of almost 200 calixarenes …

Functional protein nanostructures: a chemical toolbox

SL Kuan, FRG Bergamini, T Weil - Chemical Society Reviews, 2018 - pubs.rsc.org
Nature has evolved an optimal synthetic factory in the form of translational and
posttranslational processes by which millions of proteins with defined primary sequences …

Antiadhesive Properties of Glycoclusters against Pseudomonas aeruginosa Lung Infection

AM Boukerb, A Rousset, N Galanos… - Journal of medicinal …, 2014 - ACS Publications
Pseudomonas aeruginosa lung infections are a major cause of death in cystic fibrosis and
hospitalized patients. Treating these infections is becoming difficult due to the emergence of …

Multivalent glycocalixarenes for recognition of biological macromolecules: glycocalyx mimics capable of multitasking

F Sansone, A Casnati - Chemical Society Reviews, 2013 - pubs.rsc.org
The glycoside cluster effect, a special case of multivalency involving carbohydrates, is a
powerful tool exploited by Nature to make relatively weak interactions stronger and more …

Rational design and synthesis of optimized glycoclusters for multivalent lectin–carbohydrate interactions: influence of the linker arm

S Cecioni, JP Praly, SE Matthews… - … A European Journal, 2012 - Wiley Online Library
The design of multivalent glycoclusters requires the conjugation of biologically relevant
carbohydrate epitopes functionalized with linker arms to multivalent core scaffolds. The …