Abstract Disruption of Akt and Erk-mediated signal transduction significantly contributes in
the pathogenesis of various neurodegenerative diseases (NDs), such as Parkinson's …

Autophagy is an important cellular self-digestion and recycling pathway that helps in
maintaining cellular homeostasis. Dysregulation at various steps of the autophagic and …

Parkinson's disease (PD) is a complex neurodegenerative disorder featuring both motor and
nonmotor symptoms associated with a progressive loss of dopaminergic neurons in the …

Neuroinflammation is one of the most important processes involved in the pathogenesis of
Parkinson's disease (PD). The current concept of neuroinflammation comprises an …

Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) is a human coronavirus
(HCoV) that has created a pandemic situation worldwide as COVID‐19. This virus can …

Mucuna pruriens (Mp) is an annual and perennial legume which belongs to the family
Fabaceae having different types of therapeutic activity. Anti-oxidative, anti-inflammatory, anti …

Parkinson's disease (PD) is one of the most debilitating brain diseases. Despite the
availability of symptomatic treatments, response towards the health of PD patients remains …

Since the discovery of L-dopa in the middle of the 20th century (1960s), there is not any
neuroprotective therapy available although significant development has been made in the …

Mitochondrial dysfunction and oxidative stress characterize major factors involved in the
activation of complex processes corresponding to apoptosis‐mediated neuronal …

Parkinson's disease (PD) is a progressive nervous system disorder. Until now, the molecular
mechanism of its occurrence is not fully understood. Paraquat (PQ) was identified as a …