Exosomes are cell-derived vesicles containing heterogeneous active biomolecules such as
proteins, lipids, mRNAs, receptors, immune regulatory molecules, and nucleic acids. They …

MSCs are an extensively used cell type in clinical trials today. The initial rationale for their
clinical testing was based on their differentiation potential. However, the lack of correlation …

Advances in biomedical research have generated an unprecedented number of potential
targets for therapeutic intervention to treat disease or delay disease progression …

Exosomes are discussed as potent therapeutics due to efficient transfer of proteins, mRNA
and miRNA in selective targets. However, therapeutic exosome application requires …

Extracellular vesicles (EVs) are a heterogeneous population of secreted membrane
vesicles, with distinct biogenesis routes, biophysical properties and different functions both …

Aggregation of the microtubule associated protein Tau is associated with several
neurodegenerative disorders, including Alzheimer disease and frontotemporal dementia. In …

Exosomes are small microvesicles that are released from late endosomal compartments of
cultured cells. Recent work has shown that exosome-like vesicles are also found in many …

Exosomes are the newest family member of 'bioactive vesicles' that function to promote
intercellular communication. Exosomes are derived from the fusion of multivesicular bodies …

Prion diseases are transmissible spongiform encephalopathies (TSEs), attributed to
conformational conversion of the cellular prion protein (PrPC) into an abnormal conformer …

Extracellular vesicles, including exosomes, are small membranous vesicles released from
many biotypes, contributing to the disease progression and spreading. These extracellular …