The regulation of Reactive Oxygen Species (ROS) levels and the contribution therein from
networks regulating cell metabolism, such as autophagy and the mTOR-dependent nutrient …

Since the beginning of the discovery of microRNAs (miRs), these molecules have attracted
highly progressive attention due to their powerful regulatory roles in a broad spectrum of …

Protein tyrosine phosphatases (PTPs) play major roles in cancer and are emerging as
therapeutic targets. Recent reports suggest low–molecular weight PTP (LMPTP)—encoded …

Recent studies have reported that TUBB3 overexpression is involved in docetaxel (DTX)
resistance in prostate cancer (PCa). The aim of this study was to clarify the role of TUBB3 in …

In this work, we have developed covalent and low molecular weight docetaxel delivery
systems based on conjugation with N-acetyl-d-galactosamine and studied their properties …

Prostate cancer (PC) castration resistance has been linked to the differentiation of PC
luminal cells into hormone-refractory neuroendocrine (NE) cells. However, the molecular …

Active targeting to cancer involves exploiting specific interactions between receptors on the
surface of cancer cells and targeting moieties conjugated to the surface of vectors such that …

Objective. Curcumin, a major bioactive curcuminoid derived from the rhizome of Curcuma
longa, is known to have anticancer potential and is still under investigation. In this study, we …

Cabazitaxel (CBZ) is approved for docetaxel‐resistant castration‐resistant prostate cancer
(CRPC). However, efficacy of CBZ for CRPC is limited and there are no effective treatments …

Prostate cancer is known to have a relatively good prognosis, but long-term hormone
therapy can lead to castration-resistant prostate cancer (CRPC). Cabazitaxel, a second …