Fluorescent organic small molecule probes for bioimaging and detection applications

Y Yang, F Gao, Y Wang, H Li, J Zhang, Z Sun, Y Jiang - Molecules, 2022 - mdpi.com
The activity levels of key substances (metal ions, reactive oxygen species, reactive nitrogen,
biological small molecules, etc.) in organisms are closely related to intracellular redox …

Fluorescent probes for visualizing ROS-associated proteins in disease

H Wang, X Wang, P Li, M Dong, SQ Yao, B Tang - Chemical Science, 2021 - pubs.rsc.org
Abnormal expression of proteins, including catalytic and expression dysfunction, is directly
related to the development of various diseases in living organisms. Reactive oxygen species …

Fluorescent probes for biomolecule detection under environmental stress

X Han, Y Wang, Y Huang, X Wang, J Choo… - Journal of Hazardous …, 2022 - Elsevier
The use of fluorescent probes in visible detection has been developed over the last several
decades. Biomolecules are essential in the biological processes of organisms, and their …

Recent progress in fluorescent sensors for drug-induced liver injury assessment

J Chen, D Huang, M She, Z Wang, X Chen, P Liu… - ACS …, 2021 - ACS Publications
Drug-induced liver injury (DILI) is a persistent concern in drug discovery and clinical
medicine. The current clinical methods to assay DILI by analyzing the enzymes in serum are …

A near-infrared-II excitable pyridinium probe with 1000-fold on/off ratio for γ-glutamyltranspeptidase and cancer detection

H Shen, L Du, C Xu, B Wang, Q Zhou, R Ye… - ACS …, 2024 - ACS Publications
Activity-based detection of γ-Glutamyltranspeptidase (GGT) using near-infrared (NIR)
fluorescent probes is a promising strategy for early cancer diagnosis. Although NIR …

Prediction of Early Atherosclerotic Plaques Using a Sequence‐Activated Fluorescence Probe for the Simultaneous Detection of γ‐Glutamyl Transpeptidase and …

H Wang, X Zhang, P Li, F Huang, T Xiu… - Angewandte …, 2024 - Wiley Online Library
Atherosclerosis is a lipoprotein‐driven disease, and there is no effective therapy to reverse
atherosclerosis or existing plaques. Therefore, it is urgently necessary to create a …

The mercapturic acid pathway

PE Hanna, MW Anders - Critical reviews in toxicology, 2019 - Taylor & Francis
The mercapturic acid pathway is a major route for the biotransformation of xenobiotic and
endobiotic electrophilic compounds and their metabolites. Mercapturic acids (N-acetyl-l …

Imaging Investigation of Hepatocellular Carcinoma Progress via Monitoring γ-Glutamyltranspeptidase Level with a Near-Infrared Fluorescence/Photoacoustic Bimodal …

K Wang, XY Chen, WD Liu, Y Yue, XL Wen… - Analytical …, 2023 - ACS Publications
Hepatocellular carcinoma (HCC) is one of the main principal causes of cancer death, and
the late definite diagnosis limits therapeutic approaches in time. The early diagnosis of HCC …

Recent advances in the development of fluorescent probes for γ‐glutamyltranspeptidase

ZY Hu, XY Chen, YS Yang, SJ Wang, ZG Hu… - Coordination Chemistry …, 2024 - Elsevier
Abstract γ-Glutamyltranspeptidase (GGT) plays a significant role in the regulation of cellular
redox homeostasis and other physiological or pathophysiological processes. The over …

Constructing a novel fluorescence detection method for γ-glutamyltranspeptidase and application on visualizing liver injury

K Wang, W Wang, XY Chen, YS Yang… - Biosensors and …, 2023 - Elsevier
Liver injury is a serious threat to human health, and γ-glutamyltranspeptidase (GGT) is
proven to be one of the clinical biomarkers of liver injury. The conventional detection method …