iPS cell therapy 2.0: preparing for next‐generation regenerative medicine

KK Hui, S Yamanaka - BioEssays, 2024 - Wiley Online Library
This year marks the tenth anniversary of the world's first transplantation of tissue generated
from induced pluripotent stem cells (iPSCs). There is now a growing number of clinical trials …

Platelet generation in vivo and in vitro

JA Furniss, N Tarassova, AW Poole - Blood, 2024 - ashpublications.org
Platelets play crucial roles in hemostasis, thrombosis, and immunity, but our understanding
of their complex biogenesis (thrombopoiesis) is currently incomplete. Deeper insight into the …

PDPN/CLEC-2 axis modulates megakaryocyte subtypes in a hematopoietic stem cell-regulating megakaryocyte-dominant manner

R Nara, H Notoh, T Sasaki, N Tsukiji, T Shirai… - Thrombosis …, 2025 - Elsevier
Introduction Megakaryocytes are classified into several subtypes including LSP1-positive
immune-skewed, MYLK4-positive hematopoietic stem cell (HSC)-regulating, and BMAL1 …