A comprehensive survey on support vector machine classification: Applications, challenges and trends

J Cervantes, F Garcia-Lamont, L Rodríguez-Mazahua… - Neurocomputing, 2020 - Elsevier
In recent years, an enormous amount of research has been carried out on support vector
machines (SVMs) and their application in several fields of science. SVMs are one of the …

Advances in predicting subcellular localization of multi-label proteins and its implication for developing multi-target drugs

KC Chou - Current medicinal chemistry, 2019 - ingentaconnect.com
The smallest unit of life is a cell, which contains numerous protein molecules. Most of the
functions critical to the cell's survival are performed by these proteins located in its different …

iRNA-3typeA: identifying three types of modification at RNA's adenosine sites

W Chen, P Feng, H Yang, H Ding, H Lin… - … Therapy-Nucleic Acids, 2018 - cell.com
RNA modifications are additions of chemical groups to nucleotides or their local structural
changes. Knowledge about the occurrence sites of these modifications is essential for in …

iRNA (m6A)-PseDNC: identifying N6-methyladenosine sites using pseudo dinucleotide composition

W Chen, H Ding, X Zhou, H Lin, KC Chou - Analytical biochemistry, 2018 - Elsevier
As a prevalent post-transcriptional modification, N 6-methyladenosine (m 6 A) plays key
roles in a series of biological processes. Although experimental technologies have been …

DPP-PseAAC: a DNA-binding protein prediction model using Chou's general PseAAC

MS Rahman, S Shatabda, S Saha, M Kaykobad… - Journal of theoretical …, 2018 - Elsevier
Abstract A DNA-binding protein (DNA-BP) is a protein that can bind and interact with a DNA.
Identification of DNA-BPs using experimental methods is expensive as well as time …

SPalmitoylC-PseAAC: A sequence-based model developed via Chou's 5-steps rule and general PseAAC for identifying S-palmitoylation sites in proteins

W Hussain, YD Khan, N Rasool, SA Khan… - Analytical biochemistry, 2019 - Elsevier
S-Palmitoylation is a uniquely reversible and biologically important post-translational
modification as it plays an essential role in a variety of cellular processes including signal …

SPrenylC-PseAAC: A sequence-based model developed via Chou's 5-steps rule and general PseAAC for identifying S-prenylation sites in proteins

W Hussain, YD Khan, N Rasool, SA Khan… - Journal of theoretical …, 2019 - Elsevier
The protein prenylation (or S-prenylation) is one of the most essential modifications,
required for the association of membrane of a plethora of signalling proteins with the key …

pLoc_bal-mAnimal: predict subcellular localization of animal proteins by balancing training dataset and PseAAC

X Cheng, WZ Lin, X Xiao, KC Chou - Bioinformatics, 2019 - academic.oup.com
Motivation A cell contains numerous protein molecules. One of the fundamental goals in cell
biology is to determine their subcellular locations, which can provide useful clues about their …

Identification of 4-carboxyglutamate residue sites based on position based statistical feature and multiple classification

AA Shah, YD Khan - Scientific Reports, 2020 - nature.com
Glutamic acid is an alpha-amino acid used by all living beings in protein biosynthesis. One
of the important glutamic acid modifications is post-translationally modified 4 …

iPhosH-PseAAC: Identify phosphohistidine sites in proteins by blending statistical moments and position relative features according to the Chou's 5-step rule and …

M Awais, W Hussain, YD Khan… - … ACM transactions on …, 2019 - ieeexplore.ieee.org
Protein phosphorylation is one of the key mechanism in prokaryotes and eukaryotes and is
responsible for various biological functions such as protein degradation, intracellular …