In a normal human life span, the heart beats about 2–3 billion times. Under diseased
conditions, a heart may lose its normal rhythm and degenerate suddenly into much faster …

The global burden caused by cardiovascular disease is substantial, with heart disease
representing the most common cause of death around the world. There remains a need to …

We examine the utility of the action potential (AP) duration (APD) restitution curve slope in
predicting the onset of electrical alternans when electrotonic and memory effects are …

Pre-existing heterogeneities present in cardiac tissue are essential for maintaining the
normal electrical and mechanical functions of the heart. Exacerbation of such …

T-wave alternans, a manifestation of repolarization alternans at the cellular level, is
associated with lethal cardiac arrhythmias and sudden cardiac death. At the cellular level …

T-wave alternans (TWA) reflects every-other-beat alterations in the morphology of the
electrocardiogram ST segment or T wave in the setting of a constant heart rate, hence, in the …

A normal heartbeat is orchestrated by the stable propagation of an excitation wave that
produces an orderly contraction. In contrast, wave turbulence in the ventricles, clinically …

Self-sustained waves of electrophysiological activity can cause arrhythmia in the heart.
These reentrant excitations have been associated with spiral waves circulating around …

There has been an increasing interest in studying cardiac fibers in order to improve the
current knowledge regarding the mechanical and physiological properties of the heart …

Excitable media comprise a class of models for a wide range of physical, chemical, and
biological systems that exhibit spontaneous formation of spatial patterns. Patterns in …