Strategies and opportunities of micro/nano delivery systems for targeted therapy of ulcerative colitis: Focus on underlying mechanisms and future perspectives

Z Liu, H Liu, J Cheng, H Wang, Y Yang, J Ye… - Chinese Chemical …, 2024 - Elsevier
Ulcerative colitis (UC) is a common progressive inflammatory disease whose incidence has
increased rapidly in recent years, and can develop into colorectal cancer in severe cases …

Recent progresses of exosome–liposome fusions in drug delivery

L Zheng, B Hu, D Zhao, W Liu, Q Liu, Y Huang… - Chinese Chemical …, 2024 - Elsevier
Exosomes are membrane-bound nanoscale extracellular vesicles, which produced by
almost all organisms. Due to the excellent biocompatibility, long circulation time as well as …

In vivo detection of endogenous toxic phenolic compounds of intestine

WY Jin, JX Guo, R Tang, J Wang, H Zhao… - Journal of Hazardous …, 2024 - Elsevier
Phenol and p-cresol are two common toxic small molecules related to various diseases.
Existing reports confirmed that high L-tyrosine in the daily diet can increase the …

A “spore-like” oral nanodrug delivery platform for precision targeted therapy of inflammatory bowel disease

J Yang, K Wang, S Sun, T Pei, J Li, X Gong… - Chinese Chemical …, 2025 - Elsevier
Colon-targeted oral drug delivery systems are one of the most promising therapeutic
strategies for alleviating and curing inflammatory bowel disease (IBD), but they still face …

Simple and versatile in situ thermo-sensitive hydrogel for rectal administration of SZ-A to alleviate inflammation and repair mucosal barrier in ulcerative colitis

Y Yan, J Song, D Liu, Z Liu, J Cheng, Z Chen… - Chinese Chemical …, 2024 - Elsevier
Ulcerative colitis (UC) is a chronic inflammatory bowel disease characterized by persistent
inflammation of the colon and disrupted intestinal function. Ramulus mori (Sangzhi) …

Structure elucidation of plumerubradins A–C: Correlations between 1H NMR signal patterns and structural information of [2+ 2]-type cyclobutane derivatives

Y Xiong, LJ Hu, JG Song, D Zhang, YS Peng… - Chinese Chemical …, 2024 - Elsevier
Abstract [2+ 2]-Type cyclobutane derivatives comprise a large family of natural products with
diverse molecular architectures. However, the structure elucidation of the cyclobutane ring …

Therapeutic siRNA targeting CC chemokine receptor 2 loaded with tetrahedral framework nucleic acid alleviates neuropathic pain by regulating microglial polarization

K Wang, Y Wang, L Wang, Z Li, X Yu, X You… - Chinese Chemical …, 2025 - Elsevier
Neuropathic pain (NP) is one of the most common pathological pain types and is associated
with limited treatment options; moreover, it affects patients' quality of life and causes a heavy …

Formulation Study of Liposomes and Their Application for Inflammatory Bowel Disease Treatment

R Han - 2023 - search.proquest.com
Liposome is one of the most widely used carriers for drug delivery because of the great
biocompatibility and biodegradability. To improve treatment efficiency, liposomes are …