Photodynamic therapy is an alternative treatment mainly for cancer but also for bacterial
infections. This treatment dates back to 1900 when a German medical school graduate …

Biofilm describes a microbially-derived sessile community in which microbial cells are firmly
attached to the substratum and embedded in extracellular polymeric matrix. Microbial …

Efficient antimicrobials are urgently needed for the treatment of bacterial biofilms due to their
resistance to traditional drugs. Photodynamic therapy (PDT) is a new strategy that has been …

Highlights•PDT uses light-activated photosensitizers to produce reactive oxygen species
that kill microbial cells.•Polycationic chlorin (e6) conjugates, stable synthetic bacteriochlorins …

Highly versatile BODIPY dyes proved themselves to be very useful as photosensitizers.
These dyes can be derivatized to absorb essentially anywhere in the visible the near IR …

Photodynamic inactivation of microorganisms has gained substantial attention due to its
unique mode of action, in which pathogens are unable to generate resistance, and due to …

Reactive oxygen species (ROS) can attack a diverse range of targets to exert antimicrobial
activity, which accounts for their versatility in mediating host defense against a broad range …

Infections have been a major cause of disease throughout the history of humans on earth.
With the introduction of antibiotics, it was thought that infections had been conquered …

Antimicrobial photodynamic therapy (PDT) or photodynamic inactivation (PDI) is a new
promising strategy to eradicate pathogenic microorganisms such as Gram-positive and …

Cationic compounds are promising candidates for development of antimicrobial agents.
Positive charges attached to surfaces, particles, polymers, peptides or bilayers have been …