The surviving sepsis campaign: fluid resuscitation and vasopressor therapy research priorities in adult patients
I Lat, CM Coopersmith, D De Backer… - Intensive care medicine …, 2021 - Springer
Objective To expand upon the priorities of fluid resuscitation and vasopressor therapy
research priorities identified by a group of experts assigned by the Society of Critical Care …
research priorities identified by a group of experts assigned by the Society of Critical Care …
The timing of early antibiotics and hospital mortality in sepsis
VX Liu, V Fielding-Singh, JD Greene… - American journal of …, 2017 - atsjournals.org
Rationale: Prior sepsis studies evaluating antibiotic timing have shown mixed results.
Objectives: To evaluate the association between antibiotic timing and mortality among …
Objectives: To evaluate the association between antibiotic timing and mortality among …
A systematic review of quantitative bias analysis applied to epidemiological research
JM Petersen, LR Ranker… - International journal …, 2021 - academic.oup.com
Background Quantitative bias analysis (QBA) measures study errors in terms of direction,
magnitude and uncertainty. This systematic review aimed to describe how QBA has been …
magnitude and uncertainty. This systematic review aimed to describe how QBA has been …
Delays from first medical contact to antibiotic administration for sepsis
Objective: To evaluate the association between total medical contact, prehospital, and
emergency department delays in antibiotic administration and in-hospital mortality among …
emergency department delays in antibiotic administration and in-hospital mortality among …
Survival benefit and cost savings from compliance with a simplified 3-hour sepsis bundle in a series of prospective, multisite, observational cohorts
DE Leisman, ME Doerfler, MF Ward… - Critical care …, 2017 - journals.lww.com
Objectives: To determine mortality and costs associated with adherence to an aggressive, 3-
hour sepsis bundle versus noncompliance with greater than or equal to one bundle element …
hour sepsis bundle versus noncompliance with greater than or equal to one bundle element …
Patterns and outcomes associated with timeliness of initial crystalloid resuscitation in a prospective sepsis and septic shock cohort
DE Leisman, C Goldman, ME Doerfler… - Critical Care …, 2017 - journals.lww.com
Objectives: The objectives of this study were to 1) assess patterns of early crystalloid
resuscitation provided to sepsis and septic shock patients at initial presentation and 2) …
resuscitation provided to sepsis and septic shock patients at initial presentation and 2) …
Improving peripheral venous cannula insertion in children: a mixed methods study to develop the DIVA key
Objective To develop and validate a difficult intravenous access risk assessment and
escalation pathway, to increase first time intravenous insertion success in paediatrics …
escalation pathway, to increase first time intravenous insertion success in paediatrics …
Predictors, prevalence, and outcomes of early crystalloid responsiveness among initially hypotensive patients with sepsis and septic shock
DE Leisman, ME Doerfler, SM Schneider… - Critical care …, 2018 - journals.lww.com
Objectives: The prevalence of responsiveness to initial fluid challenge among hypotensive
sepsis patients is unclear. To avoid fluid overload, and unnecessary treatment, it is important …
sepsis patients is unclear. To avoid fluid overload, and unnecessary treatment, it is important …
Association of fluid resuscitation initiation within 30 minutes of severe sepsis and septic shock recognition with reduced mortality and length of stay
D Leisman, B Wie, M Doerfler, A Bianculli… - Annals of emergency …, 2016 - Elsevier
Study objective We evaluate the association of intravenous fluid resuscitation initiation
within 30 minutes of severe sepsis or septic shock identification in the emergency …
within 30 minutes of severe sepsis or septic shock identification in the emergency …
Recognizing and managing sepsis: what needs to be done?
Sepsis is associated with significant morbidity and mortality if not promptly recognized and
treated. Since the development of early goal-directed therapy, mortality rates have …
treated. Since the development of early goal-directed therapy, mortality rates have …