Influenza hemagglutinin structures and antibody recognition
NC Wu, IA Wilson - Cold Spring Harbor …, 2020 - perspectivesinmedicine.cshlp.org
Hemagglutinin (HA) is most abundant glycoprotein on the influenza virus surface. Influenza
HA promotes viral entry by engaging the receptor and mediating virus–host membrane …
HA promotes viral entry by engaging the receptor and mediating virus–host membrane …
GP120: target for neutralizing HIV-1 antibodies
R Pantophlet, DR Burton - Annu. Rev. Immunol., 2006 - annualreviews.org
The glycoprotein (gp) 120 subunit is an important part of the envelope spikes that decorate
the surface of HIV-1 and a major target for neutralizing antibodies. However, immunization …
the surface of HIV-1 and a major target for neutralizing antibodies. However, immunization …
[图书][B] HIV and the pathogenesis of AIDS.
JA Levy - 1994 - cabidigitallibrary.org
This book grew out of a scientific review, originally published in Microbiological Reviews. It
has been updated and expanded-now citing more than 2100 references (100 pages of the …
has been updated and expanded-now citing more than 2100 references (100 pages of the …
Tracking global patterns of N-linked glycosylation site variation in highly variable viral glycoproteins: HIV, SIV, and HCV envelopes and influenza hemagglutinin
Human and simian immunodeficiency viruses (HIV and SIV), influenza virus, and hepatitis C
virus (HCV) have heavily glycosylated, highly variable surface proteins. Here we explore N …
virus (HCV) have heavily glycosylated, highly variable surface proteins. Here we explore N …
Structures of HIV-1 gp120 envelope glycoproteins from laboratory-adapted and primary isolates
PD Kwong, R Wyatt, S Majeed, J Robinson, RW Sweet… - Structure, 2000 - cell.com
Background: The gp120 exterior envelope glycoprotein of HIV-1 binds sequentially to CD4
and chemokine receptors on cells to initiate virus entry. During natural infection, gp120 is a …
and chemokine receptors on cells to initiate virus entry. During natural infection, gp120 is a …
Neutralization escape variants of human immunodeficiency virus type 1 are transmitted from mother to infant
Maternal passive immunity typically plays a critical role in protecting infants from new
infections; however, the specific contribution of neutralizing antibodies in limiting mother-to …
infections; however, the specific contribution of neutralizing antibodies in limiting mother-to …
Targeting the glycans of glycoproteins: a novel paradigm for antiviral therapy
J Balzarini - Nature Reviews Microbiology, 2007 - nature.com
Several chronic viral infections (such as HIV and hepatitis C virus) are highly prevalent and
are a serious health risk. The adaptation of animal viruses to the human host, as recently …
are a serious health risk. The adaptation of animal viruses to the human host, as recently …
Human immunodeficiency virus type 1 V1-V2 envelope loop sequences expand and add glycosylation sites over the course of infection, and these modifications affect …
Over the course of infection, human immunodeficiency virus type 1 (HIV-1) continuously
adapts to evade the evolving host neutralizing antibody responses. Changes in the …
adapts to evade the evolving host neutralizing antibody responses. Changes in the …
V3: HIV's switch-hitter
The third variable region, V3, of the gp120 surface envelope glycoprotein is an
approximately 35-residue-long, frequently glycosylated, highly variable, disulfide-bonded …
approximately 35-residue-long, frequently glycosylated, highly variable, disulfide-bonded …
Selection for human immunodeficiency virus type 1 envelope glycosylation variants with shorter V1-V2 loop sequences occurs during transmission of certain genetic …
Designing an effective human immunodeficiency virus type 1 (HIV-1) vaccine will rely on
understanding which variants, from among the myriad of circulating HIV-1 strains, are most …
understanding which variants, from among the myriad of circulating HIV-1 strains, are most …