Abstract (S)-2-Chloro-1-(3, 4-difluorophenyl)-ethanol [(S)-CFPL] is a key chiral intermediate
in the manufacture of Ticagrelor. In this study, deep eutectic solvent (DES) was used as the …

Biocatalyzed asymmetric reduction of ketones is one of the most cost-effective and
environmentally friendly approaches for preparing chiral alcohols. However, few natural …

Studies in Natural Products Chemistry, Volume 79 covers the synthesis, testing and
recording of the medicinal properties of natural products, providing cutting-edge accounts of …

Secondary metabolites that can be produced from primary ones are not directly involved in
the normal growth, development, and reproduction of the organism. They are molecules that …

This study reported physicochemical properties of purified endo-1, 4-β-mannanase from the
wild type, Alcaligenes sp. and its most promising chemical mutant. The crude enzymes from …

Chirality plays a significant part in life since it is closely linked to carrying out the many
metabolic processes that make up a living being. Chiral secondary alcohols such as diaryl …

Microbial whole-cell catalysis has been a popular method for chiral alcohols preparation. In
this study, Cyberlindnera saturnus ZJPH1807 was successfully employed as a biocatalyst to …

Abstract The imidazo [1, 2‐a] pyridine scaffold has gained significant attention due to its
presence as a lead structure in several commercially available pharmaceuticals like …

Biocatalytic asymmetric reduction of ketone is an efficient method for the production of chiral
carbinols. The study indicates selective bioreduction of different ketones (1–8) to their …

A chemo‐enzymatic route for the preparation of (S, S)‐2, 8‐diazabicyclo [4.3. 0] nonane, a
key chiral intermediate of Moxifloxacin, has been evaluated and improved. The activity of …