Soft drusen in age-related macular degeneration: biology and targeting via the oil spill strategies
CA Curcio - Investigative ophthalmology & visual science, 2018 - iovs.arvojournals.org
AMD is a major cause of legal blindness in older adults approachable through
multidisciplinary research involving human tissues and patients. AMD is a vascular …
multidisciplinary research involving human tissues and patients. AMD is a vascular …
Corneal transplantation
DTH Tan, JKG Dart, EJ Holland, S Kinoshita - The Lancet, 2012 - thelancet.com
Corneal transplantation or keratoplasty has developed rapidly in the past 10 years.
Penetrating keratoplasty, a procedure consisting of full-thickness replacement of the cornea …
Penetrating keratoplasty, a procedure consisting of full-thickness replacement of the cornea …
Clinical classification of age-related macular degeneration
FL Ferris III, CP Wilkinson, A Bird, U Chakravarthy… - Ophthalmology, 2013 - Elsevier
OBJECTIVE: To develop a clinical classification system for age-related macular
degeneration (AMD). DESIGN: Evidence-based investigation, using a modified Delphi …
degeneration (AMD). DESIGN: Evidence-based investigation, using a modified Delphi …
Rare variants in CFI, C3 and C9 are associated with high risk of advanced age-related macular degeneration
JM Seddon, Y Yu, EC Miller, R Reynolds, PL Tan… - Nature …, 2013 - nature.com
To define the role of rare variants in advanced age-related macular degeneration (AMD)
risk, we sequenced the exons of 681 genes within all reported AMD loci and related …
risk, we sequenced the exons of 681 genes within all reported AMD loci and related …
Age-related macular degeneration
Age-related macular degeneration is a major cause of blindness worldwide. With ageing
populations in many countries, more than 20% might have the disorder. Advanced age …
populations in many countries, more than 20% might have the disorder. Advanced age …
Choroidal thickness in polypoidal choroidal vasculopathy and exudative age-related macular degeneration
SE Chung, SW Kang, JH Lee, YT Kim - Ophthalmology, 2011 - Elsevier
PURPOSE:: To compare choroidal thickness between eyes with polypoidal choroidal
vasculopathy (PCV) and eyes with age-related macular degeneration (AMD). DESIGN …
vasculopathy (PCV) and eyes with age-related macular degeneration (AMD). DESIGN …
Genome-wide association study of advanced age-related macular degeneration identifies a role of the hepatic lipase gene (LIPC)
BM Neale, J Fagerness, R Reynolds… - Proceedings of the …, 2010 - National Acad Sciences
Advanced age-related macular degeneration (AMD) is the leading cause of late onset
blindness. We present results of a genome-wide association study of 979 advanced AMD …
blindness. We present results of a genome-wide association study of 979 advanced AMD …
Cholesterol in the retina: the best is yet to come
IA Pikuleva, CA Curcio - Progress in retinal and eye research, 2014 - Elsevier
Historically understudied, cholesterol in the retina is receiving more attention now because
of genetic studies showing that several cholesterol-related genes are risk factors for age …
of genetic studies showing that several cholesterol-related genes are risk factors for age …
Common variation in three genes, including a noncoding variant in CFH, strongly influences risk of age-related macular degeneration
Age-related macular degeneration (AMD) is a common, late-onset disease with seemingly
typical complexity: recurrence ratios for siblings of an affected individual are three-to sixfold …
typical complexity: recurrence ratios for siblings of an affected individual are three-to sixfold …
Histopathological insights into choroidal vascular loss in clinically documented cases of age-related macular degeneration
Importance Age-related macular degeneration (AMD) is a multifactorial disease with genetic
and environmental factors contributing to risk. Histopathologic changes underlying AMD are …
and environmental factors contributing to risk. Histopathologic changes underlying AMD are …