Strategies to improve retention in randomised trials
Background Poor retention of participants in randomised trials can lead to missing outcome
data which can introduce bias and reduce study power, affecting the generalisability, validity …
data which can introduce bias and reduce study power, affecting the generalisability, validity …
Patient-centred clinical trial design
Patient involvement in clinical trial design can facilitate the recruitment and retention of
participants as well as potentially increase the uptake of the tested intervention and the …
participants as well as potentially increase the uptake of the tested intervention and the …
[HTML][HTML] Effect of age, sex, and morbidity count on trial attrition: meta-analysis of individual participant level data from phase 3/4 industry funded clinical trials
Main outcome measures Association between comorbidity count (identified using medical
history or concomitant drug treatment data) and trial attrition (failure for any reason to …
history or concomitant drug treatment data) and trial attrition (failure for any reason to …
Exploring non-retention in clinical trials: a meta-ethnographic synthesis of studies reporting participant reasons for drop out
ZC Skea, R Newlands, K Gillies - BMJ open, 2019 - bmjopen.bmj.com
Objectives To undertake a meta-ethnographic synthesis of findings from primary studies
reporting qualitative data that have explored participant-reported factors influencing non …
reporting qualitative data that have explored participant-reported factors influencing non …
[HTML][HTML] Priority III: top 10 rapid review methodology research priorities identified using a James LIND alliance priority setting partnership
C Beecher, E Toomey, B Maeso, C Whiting… - Journal of Clinical …, 2022 - Elsevier
Objectives A rapid review is a form of evidence synthesis considered a resource-efficient
alternative to the conventional systematic review. Despite a dramatic rise in the number of …
alternative to the conventional systematic review. Despite a dramatic rise in the number of …
Sharing space at the research table: exploring public and patient involvement in a methodology priority setting partnership
Background Public and patient involvement aims to improve research quality, relevance,
and appropriateness. Despite an increasing evidence base on the influence of public …
and appropriateness. Despite an increasing evidence base on the influence of public …
Recruitment of patients, carers and members of the public to advisory boards, groups and panels in public and patient involved health research: a scoping review
Objectives The objectives of this scoping review are to:(1) identify the distribution of and
context of the recruitment strategies used,(2) explore the facilitators, benefits, barriers and …
context of the recruitment strategies used,(2) explore the facilitators, benefits, barriers and …
Trial Forge Guidance 2: how to decide if a further Study Within A Trial (SWAT) is needed
The evidence base available to trialists to support trial process decisions—eg how best to
recruit and retain participants, how to collect data or how to share the results with …
recruit and retain participants, how to collect data or how to share the results with …
Why trials lose participants: a multitrial investigation of participants' perspectives using the theoretical domains framework
Abstract Objectives To use the Theoretical Domains Framework (TDF) to identify barriers
and enablers to participant retention in trials requiring questionnaire return and/or …
and enablers to participant retention in trials requiring questionnaire return and/or …
Recruitment and retention in clinical trials in chronic kidney disease: report from national workshops with patients, caregivers and health professionals
P Natale, T Gutman, M Howell, K Dansie… - Nephrology Dialysis …, 2020 - academic.oup.com
Background Slow recruitment and poor retention jeopardize the reliability and statistical
power of clinical trials, delaying access to effective interventions and increasing costs, as …
power of clinical trials, delaying access to effective interventions and increasing costs, as …