Snakebite envenoming represents a neglected tropical disease that has a heavy public
health impact, particularly in Asia, Africa and Latin America. A global initiative, aimed at …

The parenteral administration of antivenoms is the cornerstone of snakebite envenoming
therapy. Efforts are made to ensure that antivenoms of adequate efficacy and safety are …

The Loxosceles genus spiders (the brown spiders) are encountered in all the continents,
and the clinical manifestations following spider bites include skin necrosis with gravitational …

Snakes, scorpions, and spiders are venomous animals that pose a threat to human health,
and severe envenomings from the bites or stings of these animals must be treated with …

Animal-derived antivenoms constitute the mainstay in the therapy of snakebite envenoming.
Antivenoms are manufactured by immunizing animals, usually horses, with venoms from a …

The venom enzyme sphingomyelinase D (SMase D) in the spider family Sicariidae (brown
or fiddleback spiders [Loxosceles] and six-eyed sand spiders [Sicarius]) causes …

Spiders of the genus Loxosceles, popularly known as Brown spiders, are considered a
serious public health issue, especially in regions of hot or temperate climates, such as parts …

Brown spider envenomation results in dermonecrosis with gravitational spreading
characterized by a marked inflammatory reaction and with lower prevalence of systemic …

The Loxosceles genus represents one of the main arachnid genera of medical importance in
Brazil. Despite the gravity of Loxosceles-related accidents, just a handful of species are …

This communication reviews most of the important findings related to venom components
isolated from scorpions and spiders, mainly by means of gene cloning and expression …