A review on current status of antiviral siRNA

A Qureshi, VG Tantray, AR Kirmani… - Reviews in Medical …, 2018 - Wiley Online Library
Viral diseases like influenza, AIDS, hepatitis, and Ebola cause severe epidemics worldwide.
Along with their resistant strains, new pathogenic viruses continue to be discovered so …

Zoonotic Brazilian Vaccinia virus: from field to therapy

EG Kroon, BEF Mota, JS Abrahão, FG da Fonseca… - Antiviral Research, 2011 - Elsevier
Vaccinia virus (VACV), the prototype species of the Orthopoxvirus (OPV) genus, causes an
occupational zoonotic disease in Brazil that is primarily associated with the handling of …

Drosophila RNAi screen identifies host genes important for influenza virus replication

L Hao, A Sakurai, T Watanabe, E Sorensen, CA Nidom… - Nature, 2008 - nature.com
All viruses rely on host cell proteins and their associated mechanisms to complete the viral
life cycle. Identifying the host molecules that participate in each step of virus replication …

Animal poxvirus vaccines: a comprehensive review

V Bhanuprakash, M Hosamani… - Expert review of …, 2012 - Taylor & Francis
The family Poxviridae includes several viruses of medical and veterinary importance. Global
concerted efforts combined with an intensive mass-vaccination campaign with highly …

Suppression of Proinflammatory Signal Transduction and Gene Expression by the DualNucleic Acid Binding Domains of the Vaccinia Virus E3L Proteins

JO Langland, JC Kash, V Carter, MJ Thomas… - Journal of …, 2006 - Am Soc Microbiol
Cells have evolved elaborate mechanisms to counteract the onslaught of viral infections. To
activate these defenses, the viral threat must be recognized. Danger signals, or pathogen …

Inhibition of Monkeypox virus replication by RNA interference

A Alkhalil, S Strand, E Mucker, JW Huggins… - Virology journal, 2009 - Springer
Abstract The Orthopoxvirus genus of Poxviridae family is comprised of several human
pathogens, including cowpox (CPXV), Vaccinia (VACV), monkeypox (MPV) and Variola …

Innate immune evasion mediated by the Ambystoma tigrinum virus eukaryotic translation initiation factor 2α homologue

JK Jancovich, BL Jacobs - Journal of virology, 2011 - Am Soc Microbiol
ABSTRACT Ranaviruses (family Iridoviridae, genus Ranavirus) are large, double-stranded
DNA (dsDNA) viruses whose replication is restricted to ectothermic vertebrates. Many highly …

Aurintricarboxylic acid inhibits the early stage of vaccinia virus replication byTargeting both cellular and viral factors

C Myskiw, Y Deschambault, K Jefferies, R He… - Journal of …, 2007 - Am Soc Microbiol
Aurintricarboxylic acid (ATA) has been shown to inhibit the replication of viruses from
several different families, including human immunodeficiency virus, vesicular stomatitis …

Inhibition of type III interferon activity by orthopoxvirus immunomodulatory proteins

P Bandi, NE Pagliaccetti, MD Robek - Journal of Interferon & …, 2010 - liebertpub.com
The type III interferon (IFN) family elicits an antiviral response that is nearly identical to that
evoked by IFN-α/β. However, these cytokines (known as IFN-λ1, 2, and 3) signal through a …

Immunoinformatic and molecular docking approaches: siRNA prediction to silence cell surface binding protein of monkeypox virus

R Islam, A Shahriar, MR Uddin, N Fatema - Beni-Suef University Journal of …, 2024 - Springer
Background Monkeypox virus (MPV), an endemic pathogen in Africa, shares clinical
similarities with smallpox. Recent reports indicate a concerning increase in the number of …