[HTML][HTML] Nanopore sequencing technology, bioinformatics and applications
Rapid advances in nanopore technologies for sequencing single long DNA and RNA
molecules have led to substantial improvements in accuracy, read length and throughput …
molecules have led to substantial improvements in accuracy, read length and throughput …
Opportunities and challenges in long-read sequencing data analysis
Long-read technologies are overcoming early limitations in accuracy and throughput,
broadening their application domains in genomics. Dedicated analysis tools that take into …
broadening their application domains in genomics. Dedicated analysis tools that take into …
Highly contiguous assemblies of 101 drosophilid genomes
Over 100 years of studies in Drosophila melanogaster and related species in the genus
Drosophila have facilitated key discoveries in genetics, genomics, and evolution. While high …
Drosophila have facilitated key discoveries in genetics, genomics, and evolution. While high …
GraphAligner: rapid and versatile sequence-to-graph alignment
M Rautiainen, T Marschall - Genome biology, 2020 - Springer
Genome graphs can represent genetic variation and sequence uncertainty. Aligning
sequences to genome graphs is key to many applications, including error correction …
sequences to genome graphs is key to many applications, including error correction …
Genome of Solanum pimpinellifolium provides insights into structural variants during tomato breeding
Solanum pimpinellifolium (SP) is the wild progenitor of cultivated tomato. Because of its
remarkable stress tolerance and intense flavor, SP has been used as an important …
remarkable stress tolerance and intense flavor, SP has been used as an important …
A comprehensive evaluation of long read error correction methods
Background Third-generation single molecule sequencing technologies can sequence long
reads, which is advancing the frontiers of genomics research. However, their high error rates …
reads, which is advancing the frontiers of genomics research. However, their high error rates …
A comparative evaluation of hybrid error correction methods for error-prone long reads
S Fu, A Wang, KF Au - Genome biology, 2019 - Springer
Background Third-generation sequencing technologies have advanced the progress of the
biological research by generating reads that are substantially longer than second …
biological research by generating reads that are substantially longer than second …
Polishing de novo nanopore assemblies of bacteria and eukaryotes with FMLRC2
As the accuracy and throughput of nanopore sequencing improve, it is increasingly common
to perform long-read first de novo genome assemblies followed by polishing with accurate …
to perform long-read first de novo genome assemblies followed by polishing with accurate …
A chromosome-level genome assembly for the Silkie chicken resolves complete sequences for key chicken metabolic, reproductive, and immunity genes
F Zhu, ZT Yin, QS Zhao, YX Sun, YC Jie… - Communications …, 2023 - nature.com
A set of high-quality pan-genomes would help identify important genes that are still
hidden/incomplete in bird reference genomes. In an attempt to address these issues, we …
hidden/incomplete in bird reference genomes. In an attempt to address these issues, we …
Chromosomal level genome assembly of medicinal plant Sophora flavescens
Sophora flavescens is a medicinal plant in the genus Sophora of the Fabaceae family. The
root of S. flavescens is known in China as Kushen and has a long history of wide use in …
root of S. flavescens is known in China as Kushen and has a long history of wide use in …