[HTML][HTML] Advancing virtual bioequivalence for orally administered drug products: methodology, real-world applications and future outlook

S Kollipara, FS Martins, R Jereb, D Krajcar, T Ahmed - Pharmaceuticals, 2024 - mdpi.com
Bioequivalence studies are pivotal in generic drug development wherein therapeutic
equivalence is provided with an innovator product. However, bioequivalence studies …

Establishing mechanisms affecting the individual response to ionizing radiation

D Averbeck, S Candéias, S Chandna… - … Journal of Radiation …, 2020 - Taylor & Francis
Purpose: Humans are increasingly exposed to ionizing radiation (IR). Both low (< 100 mGy)
and high doses can cause stochastic effects, including cancer; whereas doses above 100 …

[HTML][HTML] Urinary levels of bisphenol A, F and S and markers of oxidative stress among healthy adult men: variability and association analysis

YX Wang, C Liu, Y Shen, Q Wang, A Pan, P Yang… - Environment …, 2019 - Elsevier
Abstract Background Bisphenol F (BPF) and bisphenol S (BPS) are increasingly used as
alternatives to endocrine disrupting chemical bisphenol A (BPA). Evidence from in vitro and …

[HTML][HTML] How stable is oxidative stress level? An observational study of intra-and inter-individual variability in urinary oxidative stress biomarkers of DNA, proteins, and …

MP Martinez-Moral, K Kannan - Environment international, 2019 - Elsevier
Oxidative stress in humans is affected by the health and nutritional status as well as
exposure to external environmental factors. To evaluate the effects of external factors, an …

[HTML][HTML] Could a lipid oxidative biomarker be applied to improve risk stratification in the prevention of cardiovascular disease?

MVMB Pimentel, A Bertolami, LP Fernandes… - Biomedicine & …, 2023 - Elsevier
There is significant evidence demonstrating the influence of oxidative stress on
atherosclerosis and cardiovascular diseases (CVD). However, oxidative biomarkers have …

Diagnostic performance of ultrasound attenuation imaging for assessing low-grade hepatic steatosis

JK Jang, SY Kim, IW Yoo, YB Cho, HJ Kang, DH Lee - European radiology, 2022 - Springer
Objectives To investigate the diagnostic performance of attenuation imaging (ATI) for the
assessment of low-grade hepatic steatosis using liver biopsy as the reference standard …

Associations between air pollutant exposure and renal function: a prospective study of older adults without chronic kidney disease

A Li, Y Mei, M Zhao, J Xu, R Li, J Zhao, Q Zhou… - Environmental …, 2021 - Elsevier
We used real-world exposure scenarios to evaluate the effect of six ambient air pollutant
(PM 2.5, PM 10, NO 2, SO 2, CO, and O 3) exposure on renal function among older adults …

Novel strategies for assessing associations between selenium biomarkers and cardiometabolic risk factors: concentration, visit-to-visit variability, or individual mean …

A Li, Q Zhou, Y Mei, J Zhao, M Zhao, J Xu, X Ge… - Frontiers in …, 2022 - frontiersin.org
Background and Aims Previous studies have focused only on the cardiometabolic effects of
selenium concentrations. We explored whether selenium levels and their visit-to-visit …

[HTML][HTML] Blood and urinary biomarkers of prenatal exposure to disinfection byproducts and oxidative stress: a repeated measurement analysis

C Liu, YX Wang, YJ Chen, Y Sun, LL Huang… - Environment …, 2020 - Elsevier
Background Toxicological studies have demonstrated that disinfection by-products (DBPs)
can induce oxidative stress, a proposed mechanism that is relevant to adverse birth …

Effect of occlusal splint on oxidative stress markers and psychological aspects of chronic temporomandibular pain: a randomized controlled trial

IZ Alajbeg, E Vrbanović, I Lapić, I Alajbeg, L Vuletić - Scientific reports, 2020 - nature.com
Temporomandibular disorders (TMD), when progress to a chronic state, might contribute to
psychosocial or psychological distress. This study aimed to evaluate the effect of …