Biomimetic gland models with engineered stratagems
X Lin, L Sun, M Lu, Y Zhao - Research, 2023 - spj.science.org
As extensively distributed tissues throughout the human body, glands play a critical role in
various physiological processes. Therefore, the construction of biomimetic gland models in …
various physiological processes. Therefore, the construction of biomimetic gland models in …
[HTML][HTML] Global Literature Analysis of Tumor Organoid and Tumor-on-Chip Research
Background: Tumor organoid and tumor-on-chip (ToC) platforms replicate aspects of the
anatomical and physiological states of tumors. They, therefore, serve as models for …
anatomical and physiological states of tumors. They, therefore, serve as models for …
[HTML][HTML] PLXNA1 confers enzalutamide resistance in prostate cancer via AKT signaling pathway
J Hu, J Zhang, B Han, Y Qu, Q Zhang, Z Yu, L Zhang… - Neoplasia, 2024 - Elsevier
Although targeting the androgen signaling pathway by androgen receptor (AR) inhibitors,
including enzalutamide, has shown therapeutic effectiveness, inevitable emergence of …
including enzalutamide, has shown therapeutic effectiveness, inevitable emergence of …
Patient-derived tumor xenograft study with CDK4/6 inhibitor plus AKT inhibitor for the management of metastatic castration-resistant prostate cancer
AM Kase, J Gleba, JL Miller, E Miller, J Petit… - Molecular Cancer …, 2024 - AACR
Metastatic castration-resistant prostate cancer (mCRPC) is an aggressive malignancy with
poor outcomes. To investigate novel therapeutic strategies, we characterized three new …
poor outcomes. To investigate novel therapeutic strategies, we characterized three new …
Defining the challenges and opportunities for using patient‐derived models in prostate cancer research
Background There are relatively few widely used models of prostate cancer compared to
other common malignancies. This impedes translational prostate cancer research because …
other common malignancies. This impedes translational prostate cancer research because …
Reproductive mechanisms, pathologies, and health inclusivity: insights from the 2023 Annual Meeting of the Society for Reproductive Biology
In 2023, the Society for Reproductive Biology met in Brisbane to deliver its largest scientific
program to date. Herein, we detail key areas of notable discovery across the reproductive …
program to date. Herein, we detail key areas of notable discovery across the reproductive …
Organoid Models Derived from Primary Tumors and Patient-Derive Xenograft Tumors Reflect Platinum Sensitivity of Ovarian Cancer Patients
P Nikeghbal, D Burke, MP Steinkamp - bioRxiv, 2024 - biorxiv.org
Ovarian cancer (OC) remains the deadliest gynecological cancer, primarily due to late stage
diagnosis and high rates of chemotherapy resistance and recurrence. Lack of representative …
diagnosis and high rates of chemotherapy resistance and recurrence. Lack of representative …
[PDF][PDF] FUNCTIONAL CHARACTERIZATION OF SEQUENTIAL IN VITRO MODEL OF PROSTATE TUMORIGENESIS
H Kultanen - 2024 - trepo.tuni.fi
Supervisor: Senior Research Fellow Hanna Rauhala, Doctoral researcher Konsta Kukkonen
Evaluators: Professor Vesa Hytönen & Senior Research Fellow Hanna Rauhala Prostate …
Evaluators: Professor Vesa Hytönen & Senior Research Fellow Hanna Rauhala Prostate …