Antimicrobial peptides (AMPs), critical components of the innate immune system, are widely
distributed throughout the animal and plant kingdoms. They can protect against a broad …

The development of highly effective conjugate chemistry approaches is a way to improve the
quality of drugs and of medicines. The aim of this paper is to highlight and review such …

As more antibiotics are rendered ineffective by drug-resistant bacteria, focus must be shifted
towards alternative therapies for treating infections. Although several alternatives already …

Unique coumarin conjugates with thiazolidinone as novel structural antibacterial modulators
were exploited to combat the lethal multidrug-resistant bacterial infections. Bioactivity …

Global health is increasingly being threatened by the rapid emergence of drug-resistant
microbes. The ability of these microbes to form biofilms has further exacerbated the scenario …

A novel type of coumarin thiazoles as unique multi-targeting antimicrobial agents were
developed through four steps including cyclization, nucleophilic substitution and …

With the soaring of bacterial infection and drug resistance, it is imperative to exploit new
efficient antibacterial agents. This work constructed a series of unique phenylhydrazone …

Infectious diseases continue to be one of the major contributors to human morbidity. The
rapid rate at which pathogenic microorganisms have developed resistance against frontline …

Available therapeutic strategies are urgently needed to conquer multidrug resistance of
MRSA. A visible effort was guided towards the advancement of novel antibacterial …

Main observation and conclusion The limit ability of traditional antibiotics to treat drug
resistant bacteria calls for new therapeutic alternatives. A class of unique sulfanilamide …