Hypothalamic AgRP and POMC neurons are conventionally viewed as the yin and yang of
the body's energy status, since they act in an opposite manner to modulate appetite and …

How does cognition regulate innate behaviors? While the cognitive functions of the cortex
have been extensively studied, we know much less about how cognition can regulate innate …

The optimization field suffers from the metaphor-based “pseudo-novel” or “fancy” optimizers.
Most of these cliché methods mimic animals' searching trends and possess a small …

A recent set of overused population-based methods have been published in recent years.
Despite their popularity, most of them have uncertain, immature performance, partially done …

Animals must set behavioural priority in a context-dependent manner and switch from one
behaviour to another at the appropriate moment,–. Here we probe the molecular and …

Neurons in the hypothalamic arcuate nucleus (ARC) that express agouti‐related peptide
(AgRP) govern a critical aspect of survival: the drive to eat. Equally important to survival is …

The overconsumption of highly caloric and palatable foods has caused a surge in obesity
rates in the past half century, thereby posing a healthcare challenge due to the array of …

Survival under selective pressure is driven by the ability of our brain to use sensory
information to our advantage to control physiological needs. To that end, neural circuits …

A large body of preclinical and clinical data shows that the central melanocortin system is a
promising therapeutic target for treating various metabolic disorders such as obesity and …

Our wellness relies on continuous interactions between our brain and body: different organs
relay their current state to the brain and are regulated, in turn, by descending visceromotor …