Hyperglycemia-induced oxidative stress and its role in diabetes mellitus related cardiovascular diseases

T Vanessa Fiorentino, A Prioletta… - Current …, 2013 - ingentaconnect.com
Diabetes mellitus is associated to an increased risk of cardiovascular diseases.
Hyperglycemia is an important factor in cardiovascular damage, working through different …

Studies on free radicals, antioxidants, and co-factors

K Rahman - Clinical interventions in aging, 2007 - Taylor & Francis
The interplay between free radicals, antioxidants, and co-factors is important in maintaining
health, aging and age-related diseases. Free radicals induce oxidative stress, which is …

Redox theory of aging: implications for health and disease

YM Go, DP Jones - Clinical science, 2017 - portlandpress.com
Genetics ultimately defines an individual, yet the phenotype of an adult is extensively
determined by the sequence of lifelong exposures, termed the exposome. The redox theory …

Diabetes mellitus-associated vascular impairment: novel circulating biomarkers and therapeutic approaches

D Tousoulis, N Papageorgiou, E Androulakis… - Journal of the American …, 2013 - jacc.org
It is widely accepted that diabetes mellitus (DM) impairs endothelial nitric oxide synthase
activity as well as enhances the production of reactive oxygen species, thus resulting in …

Impact of diet composition on blood glucose regulation

WR Russell, A Baka, I Björck, N Delzenne… - Critical reviews in …, 2016 - Taylor & Francis
Nutritional management of blood glucose levels is a strategic target in the prevention and
management of type 2 diabetes mellitus (T2DM). To implement such an approach, it is …

Protective mechanisms of the Mediterranean diet in obesity and type 2 diabetes

H Schröder - The Journal of nutritional biochemistry, 2007 - Elsevier
The prevalence of obesity has grown to an alarming level of at least 300 million people
worldwide. Additionally, a diabetes epidemic is underway, with an estimate of 217 million …

4‐Hydroxynonenal: A membrane lipid oxidation product of medicinal interest

G Poli, RJ Schaur, WG Siems… - Medicinal research …, 2008 - Wiley Online Library
A comprehensive focus on 4‐hydroxynonenal (HNE) as candidate molecule in a variety of
pathophysiological conditions occurring in humans is here provided. Despite an active, now …

Basic mechanisms of oxidative stress and reactive oxygen species in cardiovascular injury

CA Papaharalambus, KK Griendling - Trends in cardiovascular medicine, 2007 - Elsevier
The development of vascular disease has its origins in an initial insult to the vessel wall by
biological or mechanical factors. The disruption of homeostatic mechanisms leads to …

Antioxidants in the treatment of diabetes

S Golbidi, S Alireza Ebadi, I Laher - Current diabetes reviews, 2011 - ingentaconnect.com
Diabetes is a chronic metabolic disorder that continues to present as a major health problem
worldwide. It is characterized by absolute or relative deficiencies in insulin secretion and/or …

Fontes vegetais naturais de antioxidantes

AC Oliveira, IB Valentim, MOF Goulart, CA Silva… - Química …, 2009 - SciELO Brasil
Growing knowledge on the health-promoting impact of antioxidants in everyday foods,
combined with the assumption that a number of common synthetic preservatives may have …