Dental enamel is the hardest and most mineralized tissue in extinct and extant vertebrate
species and provides maximum durability that allows teeth to function as weapons and/or …

RUNX2 is a multifunctional transcription factor that controls skeletal development by
regulating the differentiation of chondrocytes and osteoblasts and the expression of many …

During mammalian tooth development, the oral ectoderm and mesenchyme coordinate their
growth and differentiation to give rise to organs with precise shapes, sizes and functions …

The biomineralization of the dental enamel matrix with a carbonated hydroxyapatite mineral
generates one of the most remarkable examples of a vertebrate mineralized tissue. Recent …

This review focuses on recent discoveries and delves in detail about what is known about
each of the proteins (amelogenin, ameloblastin, and enamelin) and proteinases (matrix …

A wealth of information has recently become available on the molecular signals that are
required to form and pattern the dentition in the mouse, shedding light on how important …

Biomineralization can be considered as nature's strategy to produce and sustain
biominerals, primarily via creation of hard tissues for protection and support. This review …

Regenerative medicine is based on stem cells, signals, and scaffolds. Dental pulp tissue has
the potential to regenerate dentin in response to noxious stimuli, such as caries. The …

Odontoblasts are specialized cells that produce dentin and exhibit unique morphological
characteristics; ie, they extend cytoplasmic processes into dentinal tubules. While …

The odontogenic and osteogenic potential of dental pulp stem cells (DPSCs) and stem cells
from human exfoliated deciduous tooth (SHED) have been shown clearly by various in vitro …