The airway epithelium protects us from environmental insults, which we encounter with
every breath. Not only does it passively filter large particles, it also senses potential danger …

Allergic bronchial asthma is a chronic disease of the airways that is characterized by
symptoms like respiratory distress, chest tightness, wheezing, productive cough, and acute …

abstract Bronchial asthma is characterized by persistent cough, increased sputum, and
repeated wheezing. The pathophysiology underlying these symptoms is the hyper …

Airway epithelial cells form a barrier to the outside world and are at the front line of mucosal
immunity. Epithelial apical junctional complexes are multiprotein subunits that promote cell …

Asthma is a T lymphocyte–controlled disease of the airway wall caused by inflammation,
overproduction of mucus and airway wall remodeling leading to bronchial hyperreactivity …

Orchestrating when and how the cutaneous innate immune system should respond to
commensal or pathogenic microbes is a critical function of the epithelium. The cutaneous …

Emerging evidence indicates that airway epithelial barrier function is compromised in
asthma, a disease characterized by Th2-skewed immune response against inhaled …

Epithelial permeability is a hallmark of mucosal inflammation, but the molecular mechanisms
involved remain poorly understood. A key component of the epithelial barrier is the apical …

Atopic dermatitis (AD) is characterized by epidermal tight junction (TJ) defects and a
propensity for Staphylococcus aureus skin infections. S. aureus is sensed by many pattern …

Models of the outer epithelia of the human body-namely the skin, the intestine and the lung-
have found valid applications in both research and industrial settings as attractive …