Double nexus—Doublesex is the connecting element in sex determination

EC Verhulst, L van de Zande - Briefings in functional genomics, 2015 - academic.oup.com
In recent years, our knowledge of the conserved master-switch gene doublesex (dsx) and its
function in regulating the development of dimorphic traits in insects has deepened …

The replaceable master of sex determination: bottom-up hypothesis revisited

MC Adolfi, A Herpin, M Schartl - … Transactions of the …, 2021 - royalsocietypublishing.org
Different group of vertebrates and invertebrates demonstrate an amazing diversity of gene
regulations not only at the top but also at the bottom of the sex determination genetic …

Genome-wide identification, phylogeny, and expression profile of the Dmrt (Doublesex and Mab-3 related transcription factor) gene family in channel catfish (Ictalurus …

S Xu, S Zhang, W Zhang, H Liu, M Wang… - Frontiers in …, 2022 - frontiersin.org
The Dmrt (Doublesex and Mab-3 related transcription factor) gene family is a class of crucial
transcription factors characterized by a conserved DM domain related to sex determination …

Identification and Characterization of the DMRT11E Gene in the Oriental River Prawn Macrobrachium nipponense

Y Wang, S Jin, H Fu, H Qiao, S Sun, W Zhang… - International Journal of …, 2019 - mdpi.com
The doublesex and mab-3 related transcription factor (DMRT) gene family involvement in
sex development is widely conserved from invertebrates to humans. In this study, we …

Comprehensive analysis of DMRT3 as a potential biomarker associated with the immune infiltration in a pan-cancer analysis and validation in lung adenocarcinoma

D Yang, M Liu, J Jiang, Y Luo, Y Wang, H Chen, D Li… - Cancers, 2022 - mdpi.com
Simple Summary Doublesex and Mab-3 related Transcription Factor 3 (DMRT3) is
associated with the prognosis of some tumors. It is possible to explore the mechanisms and …

Comparative transcriptome analysis of the differentiating gonads in Scatophagus argus

UF Mustapha, YX Peng, YQ Huang, D Assan… - Frontiers in Marine …, 2022 - frontiersin.org
The reproductive-related studies, including genetic and genomic such as gonadal
transcriptome analyses, have previously focused on the adult spotted scat, with little …

Evolutionary transition of doublesex regulation from sex-specific splicing to male-specific transcription in termites

S Miyazaki, K Fujiwara, K Kai, Y Masuoka, H Gotoh… - Scientific reports, 2021 - nature.com
The sex determination gene doublesex (dsx) encodes a transcription factor with two
domains, oligomerization domain 1 (OD1) and OD2, and is present throughout insects. Sex …

Genome-wide identification, phylogeny and expressional profile of the Dmrt gene family in Chinese sturgeon (Acipenser sinensis)

Y Hu, R Tan, X Zhu, B Wang, J Wang, B Guo, Y Li… - Scientific Reports, 2024 - nature.com
Chinese sturgeon Dmrt gene family was identified and characterized for the first time. A total
of 5 putative Dmrt genes were identified. The gene structure, conserved protein domain and …

Independent evolution for sex determination and differentiation in the DMRT family in animals

S Mawaribuchi, Y Ito, M Ito - Biology Open, 2019 - journals.biologists.com
Some DMRT family genes including arthropod dsx, nematode mab-3, and vertebrate dmrt1
are involved in sex determination and/or differentiation in bilaterian animals. Although there …

Genome-wide investigation of the DMRT gene family sheds new insight into the regulation of sex differentiation in spotted knifejaw (Oplegnathus punctatus) with …

H Zhao, Y Xiao, Z Xiao, Y Wu, Y Ma, J Li - International Journal of …, 2024 - Elsevier
The role of the DMRT family in male sex determination and differentiation is significant, but
its regulatory role in spotted knifejaw with Y fusion chromosomes remains unclear. Through …