Intratumoral microbiota: roles in cancer initiation, development and therapeutic efficacy

L Yang, A Li, Y Wang, Y Zhang - Signal transduction and targeted …, 2023 - nature.com
Microorganisms, including bacteria, viruses, fungi, and other eukaryotes, play critical roles in
human health. An altered microbiome can be associated with complex diseases …

Intratumoural microbiota: a new frontier in cancer development and therapy

Y Cao, H Xia, X Tan, C Shi, Y Ma, D Meng… - … and Targeted Therapy, 2024 - nature.com
Human microorganisms, including bacteria, fungi, and viruses, play key roles in several
physiological and pathological processes. Some studies discovered that tumour tissues …

Intratumoral microbiota as a target for advanced cancer therapeutics

F Peng, M Hu, Z Su, L Hu, L Guo, K Yang - Advanced Materials, 2024 - Wiley Online Library
In recent years, advancements in microbial sequencing technology have sparked an
increasing interest in the bacteria residing within solid tumors and its distribution and …

[HTML][HTML] Intratumor microbiota in cancer pathogenesis and immunity: from mechanisms of action to therapeutic opportunities

M Wang, F Yu, P Li - Frontiers in Immunology, 2023 - frontiersin.org
Microbial species that dwell human bodies have profound effects on overall health and
multiple pathological conditions. The tumor microenvironment (TME) is characterized by …

The Disease with a Thousand Faces and the Human Microbiome—A Physiopathogenic Intercorrelation in Pediatric Practice

VV Lupu, LI Butnariu, S Fotea, ID Morariu, MC Badescu… - Nutrients, 2023 - mdpi.com
Numerous interrelationships are known in the literature that have the final effect of
unmasking or influencing various pathologies. Among these, the present article aims to …

The role of the gut microbiota in gastric cancer: the immunoregulation and immunotherapy

M Wang, G Yang, Y Tian, Q Zhang, Z Liu… - Frontiers in …, 2023 - frontiersin.org
Gastric cancer (GC) is one of the most common cancers, leading to the deaths of millions of
people worldwide. Therefore, early detection and effective therapeutic strategies are of great …

Intratumoural microbiome can predict the prognosis of hepatocellular carcinoma after surgery

L Sun, X Ke, A Guan, B Jin, J Qu… - Clinical and …, 2023 - Wiley Online Library
Background The dismal prognosis of hepatocellular carcinoma (HCC) is closely associated
with characteristics of the tumour microenvironment (TME). Recent studies have confirmed …

Single-cell sequencing to multi-omics: Technologies and applications

X Wu, X Yang, Y Dai, Z Zhao, J Zhu, H Guo, R Yang - Biomarker Research, 2024 - Springer
Cells, as the fundamental units of life, contain multidimensional spatiotemporal information.
Single-cell RNA sequencing (scRNA-seq) is revolutionizing biomedical science by …

A Putative Role of Candida albicans in Promoting Cancer Development: A Current State of Evidence and Proposed Mechanisms

J Talapko, T Meštrović, B Dmitrović, M Juzbašić… - Microorganisms, 2023 - mdpi.com
Candida albicans is a commensal fungal species that commonly colonizes the human body,
but it is also a pervasive opportunistic pathogen in patients with malignant diseases. A …

Leveraging the intratumoral microbiota to treat human cancer: are engineered exosomes an effective strategy?

J Qiu, Y Jiang, N Ye, G Jin, H Shi, D Qian - Journal of translational …, 2024 - Springer
Cancer remains a leading cause of global mortality. The tumor microbiota has increasingly
been recognized as a key regulator of cancer onset and progression, in addition to shaping …