Background Indomethacin is used as standard therapy to close a patent ductus arteriosus
(PDA) but is associated with reduced blood flow to several organs. Ibuprofen, another cyclo …

Background Patent ductus arteriosus (PDA) complicates the clinical course of preterm
infants and increases the risk of adverse outcomes. Indomethacin has been the standard …

Background Indomethacin is used as standard therapy to close a patent ductus arteriosus
(PDA) but is associated with reduced blood flow to several organs. Ibuprofen, another cyclo …

A practical and reproducible high-performance liquid chromatographic method using normal
solid-phase extraction has been developed for the simultaneous analysis of twelve non …

A novel chemiluminescent method using flow injection has been investigated for the rapid
and sensitive determination of flufenamic and mefenamic acids. The method is based on a …

Mefenamic acid and indomethacin, medicaments belonging to the group of non-steroidal
anti-inflammatory agents, were determined separately and simultaneously at anodically …

A simple, rapid and specific method for analysis of mefenamic acid (I) in serum by a
sensitive high-performance liquid chromatography is described. Only 70μl of serum and a …

Terbium sensitized fluorescence was used to develop a sensitive and simple
spectrofluorimetric method for the determination of the anthranilic acid derivatives …

Indomethacin forms by decomposition two degradation products: 4-chlorobenzoic acid and
5-methoxy-2-methylindoleacetic acid. They have to be monitored together with an active …

Nonsteroidal anti-inflammatory drugs (NSAIDs) are the first choice of treatment for rheumatic
disorders and other degenerative inflammatory diseases. One of them, indomethacin …