The number one cause of human fetal death are defects in heart development. Because the
human embryonic heart is inaccessible and the impacts of mutations, drugs, and …

Branchiomeric muscles of the head and neck originate in a population of cranial mesoderm
termed cardiopharyngeal mesoderm that also contains progenitor cells contributing to …

For decades, limb development has been a paradigm of three-dimensional patterning.
Moreover, as the limb muscles and the other tissues of the limb's musculoskeletal system …

The heart develops from 2 sources of mesoderm progenitors, the first and second heart field
(FHF and SHF). Using a single-cell transcriptomic assay combined with genetic lineage …

Somite formation is foundational to creating the vertebrate segmental body plan. Here, we
describe three transcriptional trajectories toward somite formation in the early mouse …

Cardiopharyngeal mesoderm contributes to the formation of the heart and head muscles.
However, the mechanisms governing cardiopharyngeal mesoderm specification remain …

Abstract Background Circular RNA (circRNA) is produced during the splicing of mRNA (in
addition to linear splicing) and is part of the gene regulatory network. The temporal …

The evolution of vertebrates from an ancestral chordate was accompanied by the acquisition
of a predatory lifestyle closely associated to the origin of a novel anterior structure, the highly …

A great many articles discuss the histological aspects of fascial tissue in detail, but at the
same time, there are many contradictions within the literature. In addition, there is a paucity …

Skeletal muscle derives from dorsal mesoderm formed during vertebrate gastrulation.
Fibroblast growth factor (Fgf) signalling cooperates with Tbx transcription factors to promote …