Worldwide Prevalence of mcr-mediated Colistin-Resistance Escherichia coli in Isolates of Clinical Samples, Healthy Humans, and Livestock—A Systematic Review …

C Bastidas-Caldes, JH de Waard, MS Salgado… - Pathogens, 2022 - mdpi.com
Background: Antimicrobial resistance is a serious public-health problem throughout the
world. Escherichia coli, the most common Gram-negative microorganism, has developed …

Global epidemiology, genetic environment, risk factors and therapeutic prospects of mcr genes: A current and emerging update

M Mmatli, NM Mbelle, J Osei Sekyere - Frontiers in Cellular and …, 2022 - frontiersin.org
Background Mobile colistin resistance (mcr) genes modify Lipid A molecules of the
lipopolysaccharide, changing the overall charge of the outer membrane. Results and …

Knowledge, attitude, and practices on antimicrobial use and antimicrobial resistance among commercial poultry farmers in Bangladesh

MM Hassan, MA Kalam, MA Alim, S Shano… - Antibiotics, 2021 - mdpi.com
Antimicrobial resistance (AMR) has become an emerging health issue globally, posing a
threat to zoonotic pathogens and foodborne diseases. In Bangladesh, the poultry sector …

International manufacturing and trade in colistin, its implications in colistin resistance and One Health global policies: a microbiological, economic, and …

M Umair, B Hassan, R Farzana, Q Ali, K Sands… - The Lancet …, 2023 - thelancet.com
Background The emergence of colistin-resistant Enterobacterales is a global public health
concern, yet colistin is still widely used in animals that are used for food as treatment …

Antibiotic usage and resistance in food animal production: what have we learned from Bangladesh?

S Chowdhury, S Ghosh, MA Aleem, S Parveen… - Antibiotics, 2021 - mdpi.com
Irrational and inappropriate use of antibiotics in commercial chicken and aquaculture
industries can accelerate the antibiotic resistance process in humans and animals. In …

Liposomes co‐delivering curcumin and colistin to overcome colistin resistance in bacterial infections

C Qin, N Tang, Y Gan, H Zhao, Y Li… - Advanced …, 2023 - Wiley Online Library
Antibiotic colistin is the last line of defense against multidrug‐resistant (MDR) Gram‐
negative bacterial infections. Emergence of colistin resistance in microbes is a critical …

Mobile Colistin Resistance (mcr) Gene-Containing Organisms in Poultry Sector in Low- and Middle-Income Countries: Epidemiology, Characteristics, and One Health …

MU Anyanwu, IF Jaja, COR Okpala, EO Njoga… - Antibiotics, 2023 - mdpi.com
Mobile colistin resistance (mcr) genes (mcr-1 to mcr-10) are plasmid-encoded genes that
threaten the clinical utility of colistin (COL), one of the highest-priority critically important …

A 6-Year Update on the Diversity of Methicillin-Resistant Staphylococcus aureus Clones in Africa: A Systematic Review

OU Lawal, O Ayobami, A Abouelfetouh… - Frontiers in …, 2022 - frontiersin.org
Background Methicillin-resistant Staphylococcus aureus (MRSA) is a leading cause of
hospital-associated (HA) and community-associated (CA) infections globally. The multi-drug …

[HTML][HTML] Review of antibiotic use and resistance in food animal production in WHO South-East Asia Region

H Malik, R Singh, S Kaur, P Dhaka, JS Bedi… - Journal of Infection and …, 2023 - Elsevier
Antimicrobial resistance is an emerging global threat to public health. The resistant bacteria
in food animals can be transferred to humans through the food chain. Limited information on …

Structural biology of MCR-1-mediated resistance to polymyxin antibiotics

IC Materon, T Palzkill - Current Opinion in Structural Biology, 2023 - Elsevier
Polymyxins, a last resort antibiotic, target the outer membrane of pathogens and are used to
address the increasing prevalence of multidrug-resistant Gram-negative bacteria. The …