The cytoskeleton in spermatogenesis

JEM Dunleavy, MK O'Bryan, PG Stanton… - …, 2019 - rep.bioscientifica.com
As germ cells progress through spermatogenesis, they undergo a dramatic transformation,
wherein a single, diploid spermatogonial stem cell ultimately produces thousands of highly …

[HTML][HTML] KIFC1: a promising chemotherapy target for cancer treatment?

YX Xiao, WX Yang - Oncotarget, 2016 - ncbi.nlm.nih.gov
The kinesin motor KIFC1 has been suggested as a potential chemotherapy target due to its
critical role in clustering of the multiple centrosomes found in cancer cells. In this regard …

Kinesins in spermatogenesis

DD Ma, DH Wang, WX Yang - Biology of Reproduction, 2017 - academic.oup.com
Kinesins are essential for the proper function of many types of polar cells, including
epithelial cells, neurons, and sperm. Spermatogenesis is closely associated with many …

The role of actin and myosin during spermatogenesis

X Sun, T Kovacs, YJ Hu, WX Yang - Molecular biology reports, 2011 - Springer
Spermatogenesis is a transitionary process in which the diploid spermatogonia transform
into haploid mature spermatozoa. Actin and myosin have been implicated in various aspects …

The acroframosome-acroplaxome-manchette axis may function in sperm head shaping and male fertility

YL Wei, WX Yang - Gene, 2018 - Elsevier
Sperm malformation is one of the main reasons for male infertility, but the precise
mechanisms of this process remain undiscovered. The major process of spermiogenesis is …

Acroframosome-Dependent KIFC1 Facilitates Acrosome Formation during Spermatogenesis in the Caridean Shrimp Exopalaemon modestus

CC Hou, WX Yang - PLoS One, 2013 - journals.plos.org
Background Acrosome formation and nuclear shaping are the main events in
spermatogenesis. During spermiogenesis in Exopalaemon modestus, a unique microtubular …

Myosin superfamily: The multi-functional and irreplaceable factors in spermatogenesis and testicular tumors

YR Li, WX Yang - Gene, 2016 - Elsevier
Spermatogenesis is a fundamental process in sexual development and reproduction, in
which the diploid spermatogonia transform into haploid mature spermatozoa. This process is …

Co-expression network analysis identifies gonad- and embryo-associated protein modules in the sentinel species Gammarus fossarum

D Degli Esposti, C Almunia, MA Guery, N Koenig… - Scientific reports, 2019 - nature.com
Next generation sequencing and mass spectrometry technologies have recently expanded
the availability of whole transcriptomes and proteomes beyond classical model organisms in …

Myosin Va Participates in Acrosomal Formation and Nuclear Morphogenesis during Spermatogenesis of Chinese Mitten Crab Eriocheir sinensis

X Sun, Y He, L Hou, WX Yang - PLoS One, 2010 - journals.plos.org
Background The Chinese mitten crab Eriocheir sinensis belongs to the Class Crustacea,
Decapoda, Brachyura. The spermatozoon of this species is of aflagellated type, it has a …

Characterization and expression pattern of KIFC1-like kinesin gene in the testis of the Macrobrachium nipponense with discussion of its relationship with structure …

YT Wang, H Mao, CC Hou, X Sun, DH Wang… - Molecular biology …, 2012 - Springer
Spermiogenesis is a developmental process undergoing continuous differentiation to drive a
diploid spermatogonium towards a haploid sperm cell. This striking transformation from …