Hepatocellular carcinoma: a review

J Balogh, D Victor III, EH Asham… - Journal of …, 2016 - Taylor & Francis
Hepatocellular carcinoma (HCC) is the most common primary liver malignancy and is a
leading cause of cancer-related death worldwide. In the United States, HCC is the ninth …

Heterogeneity of patients with intermediate (BCLC B) Hepatocellular Carcinoma: proposal for a subclassification to facilitate treatment decisions

L Bolondi, A Burroughs, JF Dufour… - Seminars in liver …, 2012 - thieme-connect.com
The intermediate stage of hepatocellular carcinoma (HCC) comprises a highly
heterogeneous patient population and therefore poses unique challenges for therapeutic …

System analysis based on the cuproptosis-related genes identifies LIPT1 as a novel therapy target for liver hepatocellular carcinoma

C Yan, Y Niu, L Ma, L Tian, J Ma - Journal of Translational Medicine, 2022 - Springer
Background Liver hepatocellular carcinoma (LIHC) ranks sixth among the most common
types of cancer with a high mortality rate. Cuproptosis is a newly discovered type of cell …

Circulating exosomal noncoding RNAs as prognostic biomarkers in human hepatocellular carcinoma

YR Lee, G Kim, WY Tak, SY Jang… - … journal of cancer, 2019 - Wiley Online Library
Exosomal noncoding RNAs (ncRNAs) have unique expression profiles reflecting the
characteristics of a tumor, and their role in tumor progression and metastasis is emerging …

Predicting survival after liver transplantation in patients with hepatocellular carcinoma beyond the Milan criteria: a retrospective, exploratory analysis

V Mazzaferro, JM Llovet, R Miceli, S Bhoori… - The lancet …, 2009 - thelancet.com
Background Patients undergoing liver transplantation for hepatocellular carcinoma within
the Milan criteria (single tumour≤ 5 cm in size or≤ 3 tumours each≤ 3 cm in size, and no …

Increased intratumoral IL-17-producing cells correlate with poor survival in hepatocellular carcinoma patients

JP Zhang, J Yan, J Xu, XH Pang, MS Chen, L Li… - Journal of …, 2009 - Elsevier
BACKGROUND/AIMS: To characterize IL-17-producing cells, a newly defined T helper cell
subset with potent pro-inflammatory properties, in hepatocellular carcinoma (HCC) and to …

[HTML][HTML] Chemotherapy for hepatocellular carcinoma: The present and the future

M Le Grazie, MR Biagini, M Tarocchi… - World journal of …, 2017 - ncbi.nlm.nih.gov
Hepatocellular carcinoma (HCC) is the most common primary tumor of the liver. Its
relationship to chronic liver diseases, in particular cirrhosis, develops on a background of …

miR-375 inhibits autophagy and reduces viability of hepatocellular carcinoma cells under hypoxic conditions

Y Chang, W Yan, X He, L Zhang, C Li, H Huang… - Gastroenterology, 2012 - Elsevier
BACKGROUND & AIMS: Tumor cells survive hypoxic conditions by inducing autophagy. We
investigated the roles of microRNAs (miRNAs) in regulating autophagy of hepatocellular …

Tumor promotion via injury-and death-induced inflammation

A Kuraishy, M Karin, SI Grivennikov - Immunity, 2011 - cell.com
Inhibition of programmed cell death is considered to be a major aspect of tumorigenesis.
Indeed, several key oncogenic transcription factors, such as NF-κB and STAT3, exert their …

Long-term impact of liver function on curative therapy for hepatocellular carcinoma: application of the ALBI grade

H Toyoda, P Lai, J O'Beirne, CC Chong… - British journal of …, 2016 - nature.com
Background: Application of curative therapy for hepatocellular carcinoma is crucially
dependent on underlying liver function. Using the recently described ALBI grade we …