The brain continuously adapts its processing machinery to behavioural demands. To
achieve this, it rapidly modulates the operating mode of cortical circuits, controlling the way …

Switches between different behavioral states of the animal are associated with prominent
changes in global brain activity, between sleep and wakefulness or from inattentive to …

The basal forebrain provides the primary source of cholinergic input to the cortex, and it has
a crucial function in promoting wakefulness and arousal. However, whether rapid changes …

Studies of visual processing in rodents have conventionally been performed on
anesthetized animals, precluding examination of the effects of behavior on visually evoked …

To increase computational flexibility, the processing of sensory inputs changes with
behavioural context. In the visual system, active behavioural states characterized by motor …

The mouse is emerging as an important model for understanding how sensory neocortex
extracts cues to guide behavior, yet little is known about how these cues are processed …

The thalamus is classically viewed as passively relaying information to the cortex. However,
there is growing evidence that the thalamus actively regulates information transmission to …

The nucleus basalis of the basal forebrain is an essential component of the
neuromodulatory system controlling the behavioral state of an animal and it is thought to be …

Pupil size is a widely used metric of brain state. It is one of the few signals originating from
the brain that can be readily monitored with low-cost devices in basic science, clinical, and …

The highly interconnected local and large-scale networks of the neocortical sheet rapidly
and dynamically modulate their functional connectivity according to behavioral demands …