The bioprinting roadmap

W Sun, B Starly, AC Daly, JA Burdick, J Groll… - …, 2020 - iopscience.iop.org
This bioprinting roadmap features salient advances in selected applications of the technique
and highlights the status of current developments and challenges, as well as envisioned …

Skin-on-a-chip models: General overview and future perspectives

I Risueño, L Valencia, JL Jorcano, D Velasco - APL bioengineering, 2021 - pubs.aip.org
Over the last few years, several advances have been made toward the development and
production of in vitro human skin models for the analysis and testing of cosmetic and …

Chronic wound healing models

K Flynn, NN Mahmoud, S Sharifi, LJ Gould… - ACS Pharmacology & …, 2023 - ACS Publications
In this paper, we review and analyze the commonly available wound healing models
reported in the literature and discuss their advantages and issues, considering their …

Microfluidic skin‐on‐a‐chip models: Toward biomimetic artificial skin

E Sutterby, P Thurgood, S Baratchi, K Khoshmanesh… - Small, 2020 - Wiley Online Library
The role of skin in the human body is indispensable, serving as a barrier, moderating
homeostatic balance, and representing a pronounced endpoint for cosmetics and …

Three-dimensional cell cultures: the bridge between in vitro and in vivo models

O Urzì, R Gasparro, E Costanzo, A De Luca… - International Journal of …, 2023 - mdpi.com
Although historically, the traditional bidimensional in vitro cell system has been widely used
in research, providing much fundamental information regarding cellular functions and …

Development of skin-on-a-chip platforms for different utilizations: Factors to be considered

J Ponmozhi, S Dhinakaran, Z Varga-Medveczky… - Micromachines, 2021 - mdpi.com
There is increasing interest in miniaturized technologies in diagnostics, therapeutic testing,
and biomedicinal fundamental research. The same is true for the dermal studies in topical …

Microfluidic fabrication of biomimetic helical hydrogel microfibers for blood‐vessel‐on‐a‐chip applications

L Jia, F Han, H Yang, G Turnbull… - Advanced …, 2019 - Wiley Online Library
Nature has created many perfect helical microstructures, including DNA, collagen fibrils, and
helical blood vessels, to achieve unique physiological functions. While previous studies …

Advancements in extracellular matrix-based biomaterials and biofabrication of 3D organotypic skin models

SJ Phang, S Basak, HX Teh… - ACS biomaterials …, 2022 - ACS Publications
Over the last decades, three-dimensional (3D) organotypic skin models have received
enormous attention as alternative models to in vivo animal models and in vitro two …

Barrier-on-a-chip with a modular architecture and integrated sensors for real-time measurement of biological barrier function

P Zoio, S Lopes-Ventura, A Oliva - Micromachines, 2021 - mdpi.com
Biological barriers are essential for the maintenance of organ homeostasis and their
dysfunction is responsible for many prevalent diseases. Advanced in vitro models of …

A perfusable vascularized full-thickness skin model for potential topical and systemic applications

S Salameh, N Tissot, K Cache, J Lima, I Suzuki… - …, 2021 - iopscience.iop.org
Vascularization of reconstructed tissues is one of the remaining hurdles to be considered to
improve both the functionality and viability of skin grafts and the relevance of in vitro …