The bactericidal, cell membrane–targeting lipopeptide antibiotic daptomycin (DAP) is an
important agent in treating invasive Staphylococcus aureus infections. However, there have …

Parkinson's disease (PD) and Alzheimer's disease (AD) are neurodegenerative disorders
caused by the interaction of genetic, environmental, and familial factors. These diseases …

Daptomycin is an attractive option for treating prosthetic joint infection, but the 6-mg/kg of
body weight/day dose was linked to clinical failure and emergence of resistance. Using a …

Craniotomy involves the removal of a skull fragment to access the brain, such as during
tumor or epilepsy surgery, which is immediately replaced intraoperatively. The infection …

Biofilm-associated infections with Staphylococcus aureus are difficult to treat even after
administration of antibiotics that according to the standard susceptibility assays are effective …

Introduction Daptomycin is a bactericidal lipopeptide antibiotic approved for the treatment of
systemic infections (ie skin and soft tissue infections, bloodstream infections, infective …

Daptomycin (DAP) is increasingly used as a part of combination therapy, particularly in
complex methicillin-resistant Staphylococcus aureus (MRSA) infections. While multiple …

The development of infections is one of the main complications in orthopaedics, especially
in the presence of implants for the osteosynthesis of compound fractures and joint …

Osteomyelitis is a serious infection predominantly caused by Gram-positive bacteria,
including methicillin-resistant Staphylococcus aureus (MRSA). Orthopaedic device-related …

Daptomycin exhibits clinical activity in the treatment of infections with Gram-positive
organisms, including infections due to methicillin-resistant Staphylococcus aureus …