Inflammation is a pivotal response to a variety of stimuli, and inflammatory molecules such
as cytokines have central roles in the pathogenesis of various diseases, including bone and …

Osteoarthritis (OA) is a prevalent disease of most mammalian species and is a significant
cause of welfare and economic morbidity in affected individuals and populations. In vitro …

Background We have recently identified interleukin 1B (IL-1B) as a potential biomarker for
predicting breast cancer patients at increased risk for developing bone metastasis. In mouse …

Immune cells play vital roles in regulating bone dynamics. Successful bone regeneration
requires a favourable osteo-immune environment. The high plasticity and diversity of …

Because of its high prevalence worldwide, osteoporosis is considered a serious public
health concern. Many known risk factors for developing osteoporosis have been identified …

Inflammation is an immediate response that plays a critical role in healing after fracture or
injury to bone. However, in certain clinical contexts, such as in inflammatory diseases or in …

Background SARS-CoV-2 is a highly infectious respiratory virus associated with coronavirus
disease (COVID-19). Discoveries in the field revealed that inflammatory conditions exert a …

Bone homeostasis, which involves formation and resorption, is an important process for
maintaining adequate bone mass in humans. Rheumatoid arthritis (RA) is an autoimmune …

Osteoporosis is a frequently observed complication in patients with chronic liver disease,
particularly liver cirrhosis and cholestatic liver diseases. In addition, osteoporosis is critical in …

Composite scaffolds of nano-hydroxyapatite (nHAp) and silk fibroin (SF) have been reported
to promote bone regeneration mainly through signaling pathways associated with cell …