Pulmonary embolism is an important clinical entity with considerable mortality despite
advances in diagnosis and treatment. In the present article, the authors offer a …

Acute myocardial infarction is defined as myocardial cell death due to prolonged myocardial
ischaemia. Cardiac troponins (cTn) are the most sensitive and specific biochemical markers …

Background This is the 2nd update to the 9th edition of these guidelines. We provide
recommendations on 17 PICO (Population, Intervention, Comparator, Outcome) questions …

Background We update recommendations on 12 topics that were in the 9th edition of these
guidelines, and address 3 new topics. Methods We generate strong (Grade 1) and weak …

Previous work has identified 6 important areas to consider when evaluating validity and bias
in studies of prognostic factors: participation, attrition, prognostic factor measurement …

The task of developing ESC Guidelines covers not only the integration of the most recent
research, but also the creation of educational tools and implementation programmes for the …

Objective To review the evidence for existing prognostic models in acute pulmonary
embolism (PE) and determine how valid and useful they are for predicting patient outcomes …

Background Low back pain is costly and disabling. Prognostic factor evidence can help
healthcare providers and patients understand likely prognosis, inform the development of …

Background—The new, high-sensitivity troponin T (hsTnT) assay may improve risk
stratification of normotensive patients with acute pulmonary embolism (PE). We externally …

Aims To assess the role of cardiac troponin T (cTnT) levels on admission using a new, highly
sensitive assay (hsTnT) in the risk assessment of normotensive patients with acute …