Molecularly targeted treatments and immunotherapy are cornerstones in oncology, with
demonstrated efficacy across different tumor types. Nevertheless, the overwhelming majority …

Immunotherapy has emerged as a promising new treatment modality for head and neck
cancer, offering the potential for targeted and effective cancer management. Squamous cell …

The substantial heterogeneity exhibited by head and neck cancer (HNC), encompassing
diverse cellular origins, anatomical locations, and etiological contributors, combined with the …

An important determinant for oral squamous cell carcinoma (OSCC) onset and outcome is
the composition of the tumor microenvironment (TME). Thus, the study of the interactions …

Head and neck squamous cell carcinoma (HNSCC) is one of the most common
malignancies globally, representing a significant public health problem with a poor …

Background and purpose Given that the intratumoral heterogeneity of head and neck
squamous cell carcinoma may be related to the local control rate of radiotherapy, the aim of …

Head and neck squamous cell carcinomas (HNSCCs) are introduced as the sixth most
common cancer in the world. Detection of predictive biomarkers improve early diagnosis …

Objective In the last three decades, there has been a surge in research on cancer organoids
using 3D culture technologies, which has resulted in the development of physiological …

The development of new anticancer therapies tends to be very slow. Although their impact
on potential candidates is confirmed in preclinical studies,∼ 95% of these new therapies are …

The strategies of future medicine are aimed to modernize and integrate quality approaches
including early molecular-genetic profiling, identification of new therapeutic targets and …