Advances in SARS-CoV-2 receptor-binding domain-based COVID-19 vaccines

X Guan, Y Yang, L Du - Expert review of vaccines, 2023 - Taylor & Francis
ABSTRACT Introduction The Coronavirus Disease 2019 (COVID-19) pandemic has caused
devastating human and economic costs. Vaccination is an important step in controlling the …

Glycosylated Delta-receptor-binding domain mucosal vaccine elicits broadly neutralizing antibodies with protection against SARS-CoV-2 challenge

X Guan, AK Verma, G Wang, J Shi, S Perlman, L Du - Iscience, 2023 - cell.com
Mucosal COVID-19 vaccines are needed to block SARS-CoV-2 infection at the mucosal site.
Intranasal delivery of a glycosylated Delta variant receptor-binding domain (Delta-RBD) …

Screening of efficient adjuvants for the RBD-based subunit vaccine of SARS-CoV-2

J Shi, Y Zhao, M Peng, S Zhu, Y Wu, R Ji, C Shen - Vaccines, 2023 - mdpi.com
The variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are more
transmissible, with a reduced sensitivity to vaccines targeting the original virus strain …

[HTML][HTML] MERS-CoV RBD-mRNA vaccine induces potent and broadly neutralizing antibodies with protection against MERS-CoV infection

W Tai, J Zheng, X Zhang, J Shi, G Wang, X Guan, J Zhu… - Virus research, 2023 - Elsevier
Middle East respiratory syndrome coronavirus (MERS-CoV), a highly pathogenic
coronavirus in the same Betacoronavirus genus and Coronaviridae family as SARS-CoV-2 …

Safety and immunogenicity following the second and third doses of the BNT162b2 mRNA COVID-19 vaccine in adolescents with juvenile-onset autoimmune …

M Heshin-Bekenstein, A Ziv, N Toplak, S Lazauskas… - Vaccines, 2023 - mdpi.com
Background: To explore the long-term safety and dynamics of the immune response induced
by the second and third doses of the BNT162b2 mRNA COVID-19 vaccine in adolescents …

[HTML][HTML] AT cell–based SARS-CoV-2 spike protein vaccine provides protection without antibodies

J Shi, J Zheng, X Zhang, W Tai, R Compas, J Deno… - JCI insight, 2024 - ncbi.nlm.nih.gov
Abstract SARS-CoV-2 spike–based vaccines are used to control the COVID-19 pandemic.
However, emerging variants have become resistant to antibody neutralization and further …

A Unique mRNA Vaccine Elicits Protective Efficacy against the SARS-CoV-2 Omicron Variant and SARS-CoV

X Guan, AK Verma, G Wang, A Roy, S Perlman, L Du - Vaccines, 2024 - mdpi.com
The highly pathogenic coronaviruses SARS-CoV-2 and SARS-CoV have led to the COVID-
19 pandemic and SARS outbreak, respectively. The receptor-binding domain (RBD) of the …

[PDF][PDF] Factores que influyen en la respuesta de anticuerpos neutralizantes al virus SARS-CoV-2 original y su variante Ómicron, un estudio basado en la población.

J Hormazabal - congreso2023.ufro.cl
Presentación de PowerPoint Page 1 Factores que influyen en la respuesta de anticuerpos
neutralizantes al virus SARSCoV-2 original y su variante Ómicron, un estudio basado en la …

[HTML][HTML] Factors influencing neutralizing antibody response to the original SARS-CoV-2 virus and the Omicron variant in a high vaccination coverage country, a …

J Hormazábal, L Nuñez-Franz, P Rubilar, M Apablaza… - Vaccine: X, 2023 - Elsevier
Objective The study compared immunity to the original SARS-CoV-2 virus (Wuhan) and the
Omicron variant using neutralizing antibodies (NAbs), that provide a good approximation of …