Artificial Intelligence revolutionizes the drug development process that can quickly identify
potential biologically active compounds from millions of candidate within a short period. The …

Docking is a computational technique that places a small molecule (ligand) in the binding
site of its macromolecular target (receptor) and estimates its binding affinity. This review …

Abstract Severe Acute Respiratory Syndrome caused by a coronavirus is a recent viral
infection. There is no scientific evidence or clinical trials to indicate that possible therapies …

Since the outbreak of the COVID-19 pandemic in December 2019 and its rapid spread
worldwide, the scientific community has been under pressure to react and make progress in …

In the present study, the silver nanoparticles (AgNPs) were synthesized from the bulbs of
Allium sativum, characterized by UV–visible spectroscopy, FT-IR, SEM, HR-TEM, EDAX …

Protein-ligand docking is a computational method for identifying drug leads. The method is
capable of narrowing a vast library of compounds down to a tractable size for downstream …

The scientific community is working against the clock to arrive at therapeutic interventions to
treat patients with COVID-19. Among the strategies for drug discovery, virtual screening …

The inhibition of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) main
protease (Mpro) and papain-like protease (PLpro) prevents viral multiplications; these viral …

The wide biological actions of triazolotriazine hybrids, benzene‐sulfonamide derivatives,
exhibit a good chance of displaying in vitro anti‐inflammatory effects. An operationally …

Approximate 70% of cobra venom is composed of cytotoxin (CTX), which is responsible for
the dermonecrotic symptoms of cobra envenomation. However, CTX is generally low in …