Epilepsy genes deliver critical insights into the molecular control of brain synchronization
and are revolutionizing our understanding and treatment of the disease. The epilepsy …

Adult mammalian neural stem cells are unique because of their properties, such as
differentiation capacity, self-renewal, quiescence, and also because they exist in specific …

Induced pluripotent stem cell (iPSC)-based technologies offer an unprecedented opportunity
to perform high-throughput screening of novel drugs for neurological and …

Stem cell-based therapy is a potential treatment for neurodegenerative diseases, but its
application to Alzheimer's disease (AD) remains limited. Brain-derived neurotrophic factor …

With 100 billion neurons and 100 trillion synapses, the human brain is not just the most
complex organ in the human body, but has also been described as “the most complex thing …

Genetic factors are central to the etiology of neurodegeneration, both as monogenic causes
of heritable disease and as modifiers of susceptibility to complex, sporadic disorders. Over …

We have designed a novel two-component matrix (SPRPix) for the encapsulation of directly
reprogrammed human neural precursor cells (drNPC). The matrix is comprised of 1) a solid …

The process of generating new neurons of different phenotype and function from
undifferentiated stem and progenitor cells starts at very early stages of development and …

Research over the last few years in cellular reprogramming has enlightened the magical
potential of microRNAs (miRNAs) in changing the cell fate from somatic to pluripotent …

High post-transplantation cell mortality is the main limitation of various approaches that are
aimed at improving regeneration of injured neural tissue by an injection of neural stem cells …