Graves' disease: Epidemiology, genetic and environmental risk factors and viruses

A Antonelli, SM Ferrari, F Ragusa, G Elia… - Best practice & research …, 2020 - Elsevier
Graves' disease (GD) is the most common cause of hyperthyroidism in developed Countries.
It is more common between 30 and 60 years; 5–10 times more frequent in women. The …

Hashimoto thyroiditis: clinical and diagnostic criteria

P Caturegli, A De Remigis, NR Rose - Autoimmunity reviews, 2014 - Elsevier
Hashimoto thyroiditis (HT), now considered the most common autoimmune disease, was
described over a century ago as a pronounced lymphoid goiter affecting predominantly …

Autoimmune thyroid disorders

A Antonelli, SM Ferrari, A Corrado… - Autoimmunity …, 2015 - Elsevier
Autoimmune thyroid diseases (AITD) result from a dysregulation of the immune system
leading to an immune attack on the thyroid. AITD are T cell-mediated organ-specific …

Mechanisms in endocrinology: autoimmune thyroid disease: old and new players

G Effraimidis, WM Wiersinga - European journal of …, 2014 - academic.oup.com
The last 10 years have seen some progress in understanding the etiology of autoimmune
thyroid disease (AITD). The female preponderance can now be explained–at least in part …

Smoking and thyroid

WM Wiersinga - Clinical endocrinology, 2013 - Wiley Online Library
Current smoking in population surveys is associated with a slight dose‐dependent fall of
serum TSH, likely secondary to a rise of serum FT 4 and FT 3 induced by activation of the …

The pathogenesis of Hashimoto's thyroiditis: further developments in our understanding

RA Ajjan, AP Weetman - Hormone and Metabolic Research, 2015 - thieme-connect.com
Hashimoto's thyroiditis (HT) is part of a spectrum of thyroid autoimmune conditions and this
review provides an update on the latest developments in the field. HT has a genetic …

Smoke and autoimmunity: The fire behind the disease

C Perricone, M Versini, D Ben-Ami, S Gertel… - Autoimmunity …, 2016 - Elsevier
The association between smoke habit and autoimmunity has been hypothesized a long time
ago. Smoke has been found to play a pathogenic role in certain autoimmune disease as it …

Mechanisms in endocrinology: the crosstalk between thyroid gland and adipose tissue: signal integration in health and disease

F Santini, P Marzullo, M Rotondi… - European journal of …, 2014 - academic.oup.com
Obesity and thyroid diseases are common disorders in the general population and they
frequently occur in single individuals. Alongside a chance association, a direct relationship …

Treatment with thyroid hormone

B Biondi, L Wartofsky - Endocrine reviews, 2014 - academic.oup.com
Thyroid hormone deficiency can have important repercussions. Treatment with thyroid
hormone in replacement doses is essential in patients with hypothyroidism. In this review …

Clinical relevance of environmental factors in the pathogenesis of autoimmune thyroid disease

WM Wiersinga - Endocrinology and metabolism, 2016 - synapse.koreamed.org
Genetic factors contribute for about 70% to 80% and environmental factors for about 20% to
30% to the pathogenesis of autoimmune thyroid disease (AITD). Relatives of AITD patients …