Most cells are polarized. Embryonic and stem cells can use their polarity to generate cell
diversity by asymmetric cell division, whereas differentiated cells use their polarity to execute …

Eukaryotic cells display a wide range of morphologies important for cellular function and
development. A particular cell shape is made via the generation of asymmetry in the …

Polarization is a fundamental cellular property, which is essential for the function of
numerous cell types. Over the past three to four decades, research using the best …

Surface receptors of animal cells, such as integrins, promote mechanosensation by forming
clusters as signaling hubs that transduce tensile forces. Walled cells of plants and fungi also …

The survival of eukaryotic organisms during environmental changes is largely dependent on
the adaptive responses elicited by signal transduction cascades, including those regulated …

The amazing structural variety of cells is matched only by their functional diversity, and
reflects the complex interplay between biochemical and mechanical regulation. How both …

How growing cells cope with size expansion while ensuring mechanical integrity is not
known. In walled cells, such as those of microbes and plants, growth and viability are both …

The cell division programme included in each cell specifies that, after anaphase, cytokinesis
completes the process of producing two cells. With the exception of plant cells, whose …

Regulation of PIPK (phosphatidylinositol phosphate kinase) and PtdIns (4, 5) P 2 signalling
by small G-proteins and their effectors is key to many biological functions. Through selective …

Polycystins are conserved mechanosensitive channels whose mutations lead to the
common human renal disorder autosomal dominant polycystic kidney disease (ADPKD) …