Genetics and epigenetics: new insight on gestational diabetes mellitus

MG Dalfrà, S Burlina, GG Del Vescovo… - Frontiers in …, 2020 - frontiersin.org
Gestational diabetes mellitus (GDM) is the most common metabolic complication of
pregnancy, with a prevalence that has increased significantly in the last decade, coming to …

NMR and pattern recognition methods in metabolomics: from data acquisition to biomarker discovery: a review

A Smolinska, L Blanchet, LMC Buydens… - Analytica chimica …, 2012 - Elsevier
Metabolomics is the discipline where endogenous and exogenous metabolites are
assessed, identified and quantified in different biological samples. Metabolites are crucial …

Metabolomic biomarkers in gestational diabetes mellitus: a review of the evidence

S Alesi, D Ghelani, K Rassie, A Mousa - International Journal of …, 2021 - mdpi.com
Gestational diabetes mellitus (GDM) is the fastest growing type of diabetes, affecting
between 2 to 38% of pregnancies worldwide, varying considerably depending on diagnostic …

New insights into gestational glucose metabolism: lessons learned from 21st century approaches

AR Angueira, AE Ludvik, TE Reddy, B Wicksteed… - Diabetes, 2015 - Am Diabetes Assoc
Pregnancy presents a unique physiological challenge that requires changes coordinated by
placentally and non–placentally derived hormones to prepare the mother for the metabolic …

Recommendations and standardization of biomarker quantification using NMR-based metabolomics with particular focus on urinary analysis

AH Emwas, R Roy, RT McKay, D Ryan… - Journal of proteome …, 2016 - ACS Publications
NMR-based metabolomics has shown considerable promise in disease diagnosis and
biomarker discovery because it allows one to nondestructively identify and quantify large …

Metabolic profiling of gestational diabetes in obese women during pregnancy

SL White, D Pasupathy, N Sattar, SM Nelson… - Diabetologia, 2017 - Springer
Aims/hypothesis Antenatal obesity and associated gestational diabetes (GDM) are
increasing worldwide. While pre-existing insulin resistance is implicated in GDM in obese …

The furan fatty acid metabolite CMPF is elevated in diabetes and induces β cell dysfunction

KJ Prentice, L Luu, EM Allister, Y Liu, LS Jun… - Cell metabolism, 2014 - cell.com
Gestational diabetes (GDM) results from failure of the β cells to adapt to increased metabolic
demands; however, the cause of GDM and the extremely high rate of progression to type 2 …

Metabolomics of human amniotic fluid and maternal plasma during normal pregnancy

M Orczyk-Pawilowicz, E Jawien, S Deja, L Hirnle… - PloS one, 2016 - journals.plos.org
Metabolic profiles of amniotic fluid and maternal blood are sources of valuable information
about fetus development and can be potentially useful in diagnosis of pregnancy disorders …

Metabolic fingerprint of gestational diabetes mellitus

D Dudzik, M Zorawski, M Skotnicki, W Zarzycki… - Journal of …, 2014 - Elsevier
Gestational Diabetes (GDM) is causing severe short-and long-term complications for mother,
fetus or neonate. As yet, the metabolic alterations that are specific for the development of …

Machine learning-based models for gestational diabetes mellitus prediction before 24–28 weeks of pregnancy: A review

D Mennickent, A Rodríguez, M Farías-Jofré… - Artificial Intelligence in …, 2022 - Elsevier
Abstract Gestational Diabetes Mellitus (GDM) is a hyperglycemia state that impairs maternal
and offspring health, short and long-term. It is usually diagnosed at 24–28 weeks of …