The effect of underweight on female and male reproduction

C Boutari, PD Pappas, G Mintziori, MP Nigdelis… - Metabolism, 2020 - Elsevier
Chronic energy deficiency can impair the hypothalamic-pituitary-gonadal (HPG) axis and
lead to hypothalamic anovulation in underweight women. This review presents the …

Role of seipin in human diseases and experimental animal models

Y Li, X Yang, L Peng, Q Xia, Y Zhang, W Huang, T Liu… - Biomolecules, 2022 - mdpi.com
Seipin, a protein encoded by the Berardinelli-Seip congenital lipodystrophy type 2 (BSCL2)
gene, is famous for its key role in the biogenesis of lipid droplets and type 2 congenital …

FAM209 associates with DPY19L2, and is required for sperm acrosome biogenesis and fertility in mice

JM Castaneda, K Shimada, Y Satouh… - Journal of Cell …, 2021 - journals.biologists.com
Infertility afflicts up to 15% of couples globally each year with men a contributing factor in
50% of these cases. Globozoospermia is a rare condition found in infertile men, which is …

Polysaccharide from Ostrea rivularis attenuates reproductive oxidative stress damage via activating Keap1-Nrf2/ARE pathway

S Li, Z Song, T Liu, J Liang, J Yuan, Z Xu, Z Sun… - Carbohydrate …, 2018 - Elsevier
The purpose of this study was to investigate the effects of Ostrea rivularis polysaccharide
(ORP) against testicular oxidative stress injury via kelch-like ECH-associated protein 1 …

[HTML][HTML] Cross-ancestry meta-genome-wide association studies provide insights to the understanding of semen traits in pigs

H Cheng, ZY Zhang, H Han, R Wei, W Zhao, YC Sun… - animal, 2024 - Elsevier
Semen traits play a crucial role in pig reproduction and fertility. However, limited data
availability hinder a comprehensive understanding of the genetic mechanisms underlying …

The transcription factor SOX30 is a key regulator of mouse spermiogenesis

D Zhang, D Xie, X Lin, L Ma, J Chen, D Zhang… - …, 2018 - journals.biologists.com
The postmeiotic development of male germ cells, also known as spermiogenesis, features
the coordinated expression of a large number of spermatid-specific genes. However, only a …

The acroframosome-acroplaxome-manchette axis may function in sperm head shaping and male fertility

YL Wei, WX Yang - Gene, 2018 - Elsevier
Sperm malformation is one of the main reasons for male infertility, but the precise
mechanisms of this process remain undiscovered. The major process of spermiogenesis is …

Loss of the seipin gene perturbs eggshell formation in Caenorhabditiselegans

X Bai, LJ Huang, SW Chen, B Nebenfuehr… - …, 2020 - journals.biologists.com
Seipin, an evolutionary conserved protein, plays pivotal roles during lipid droplet (LD)
biogenesis and is associated with various human diseases with unclear mechanisms. Here …

Different fixative methods influence histological morphology and TUNEL staining in mouse testes

H Wang, LL Yang, YL Ji, YH Chen, J Hu, C Zhang… - Reproductive …, 2016 - Elsevier
Abstract Society of Toxicologic Pathology has recommended mDF to fix testes since 2002.
However, subsequent studies showed that false TUNEL-positive cells were observed in …

Deletion of Lysophosphatidic Acid Receptor 3 (Lpar3) Disrupts Fine Local Balance of Progesterone and Estrogen Signaling in Mouse Uterus During Implantation

H Diao, R Li, AE El Zowalaty, S Xiao… - Biology of …, 2015 - academic.oup.com
Lpar3 encodes LPA3, the third G protein-coupled receptor for lysophosphatidic acid (LPA).
Lpar3−/− female mice had delayed embryo implantation. Their serum progesterone and …