Mitochondrial quality control in kidney injury and repair
C Tang, J Cai, XM Yin, JM Weinberg… - Nature Reviews …, 2021 - nature.com
Mitochondria are essential for the activity, function and viability of eukaryotic cells and
mitochondrial dysfunction is involved in the pathogenesis of acute kidney injury (AKI) and …
mitochondrial dysfunction is involved in the pathogenesis of acute kidney injury (AKI) and …
Melatonin suppresses platelet activation and function against cardiac ischemia/reperfusion injury via PPAR γ/FUNDC 1/mitophagy pathways
H Zhou, D Li, P Zhu, S Hu, N Hu, S Ma… - Journal of pineal …, 2017 - Wiley Online Library
Platelet activation is a major (patho‐) physiological mechanism that underlies
ischemia/reperfusion (I/R) injury. In this study, we explored the molecular signals for platelet …
ischemia/reperfusion (I/R) injury. In this study, we explored the molecular signals for platelet …
Considerations for studying sex as a biological variable in spinal cord injury
AN Stewart, SM MacLean, AJ Stromberg… - Frontiers in …, 2020 - frontiersin.org
In response to NIH initiatives to investigate sex as a biological variable in preclinical animal
studies, researchers have increased their focus on male and female differences in …
studies, researchers have increased their focus on male and female differences in …
The potential therapeutic role of metformin in diabetic and non-diabetic bone impairment
W Mu, G Liang, Y Feng, Y Jiang, F Qu - Pharmaceuticals, 2022 - mdpi.com
Metformin is a widely-used anti-diabetic drug in patients with type 2 diabetic mellitus (T2DM)
due to its safety and efficacy in clinical. The classic effect of metformin on lowering blood …
due to its safety and efficacy in clinical. The classic effect of metformin on lowering blood …
Platelet autophagic machinery involved in thrombosis through a novel linkage of AMPK-MTOR to sphingolipid metabolism
TY Lee, WJ Lu, CA Changou, YC Hsiung, NTT Trang… - Autophagy, 2021 - Taylor & Francis
Basal macroautophagy/autophagy has recently been found in anucleate platelets. Platelet
autophagy is involved in platelet activation and thrombus formation. However, the …
autophagy is involved in platelet activation and thrombus formation. However, the …
MiR‐144 protects the heart from hyperglycemia‐induced injury by regulating mitochondrial biogenesis and cardiomyocyte apoptosis
L Tao, X Huang, M Xu, L Yang, F Hua - The FASEB Journal, 2020 - Wiley Online Library
Several lines of evidence have revealed the potential of microRNAs (miRNAs, miRs) as
biomarkers for detecting diabetic cardiomyopathy, although their functions in hyperglycemic …
biomarkers for detecting diabetic cardiomyopathy, although their functions in hyperglycemic …
Effects of Xin-Ji-Er-Kang on heart failure induced by myocardial infarction: Role of inflammation, oxidative stress and endothelial dysfunction
J Hu, P Cheng, G Huang, G Cai, F Lian, XY Wang… - Phytomedicine, 2018 - Elsevier
Abstract Background Xin-Ji-Er-Kang (XJEK) is a Chinese herbal formula, which has been
reported to exert effective protection on cardiovascular diseases like hypertension and …
reported to exert effective protection on cardiovascular diseases like hypertension and …
Defects in the mitochondrial-tRNA modification enzymes MTO1 and GTPBP3 promote different metabolic reprogramming through a HIF-PPARγ-UCP2-AMPK axis
R Boutoual, S Meseguer, M Villarroya… - Scientific Reports, 2018 - nature.com
Human proteins MTO1 and GTPBP3 are thought to jointly catalyze the modification of the
wobble uridine in mitochondrial tRNAs. Defects in each protein cause infantile hypertrophic …
wobble uridine in mitochondrial tRNAs. Defects in each protein cause infantile hypertrophic …
Curdione inhibits thrombin-induced platelet aggregation via regulating the AMP-activated protein kinase-vinculin/talin-integrin αIIbβ3 sign pathway
H Fang, B Gao, Y Zhao, X Fang, M Bian, Q Xia - Phytomedicine, 2019 - Elsevier
Background Curdione, a sesquiterpene compound isolated from the essential oil of
Curcuma aromatica Salisb. inhibits platelet aggregation, suggesting its significant …
Curcuma aromatica Salisb. inhibits platelet aggregation, suggesting its significant …
Comparative In Vitro Toxicity Study of Docetaxel and Nanoxel, a Docetaxel-Loaded Micellar Formulation Using Cultured and Blood Cells
VQ Do, KH Park, JM Park, MY Lee - Toxicological research, 2019 - Springer
Abstract Nanoxel-PM TM (Nanoxel) is a docetaxel-loaded methoxy-poly (ethylene glycol)-
block-poly (D, L-lactide)(mPEG-PDLLA). This newly developed and marketed …
block-poly (D, L-lactide)(mPEG-PDLLA). This newly developed and marketed …